
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Disruption of the CD4-p56lck complex is required for rapid internalization of CD4 - PMC
Description:
CD4 is a cell surface glycoprotein expressed by a subset of T lymphocytes and functions to enhance T-cell activation. CD4 is noncovalently associated via the cytoplasmic domain with the protein-tyrosine kinase p56lck, a member of the src ...
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Keywords {🔍}
doi, pubmed, google, scholar, kinase, cell, plck, receptor, pmc, cytoplasmic, tyrosine, protein, immunol, biol, nlm, internalization, article, domain, activity, chem, insulin, ncbi, search, strominger, burakoff, proteintyrosine, phorbol, cells, complex, required, sleckman, phosphorylation, image, oct, free, national, disruption, cdplck, shin, surface, activation, myristate, association, requirement, references, antigen, ullrich, endocytosis, nature, apr,
Topics {✒️}
protein-tyrosine kinase activity protein-tyrosine kinase p56lck pmc beta search unique n-terminal region murine t-cell hybridoma tyrosine kinase activity unique amino-terminal domain protein-tyrosine kinase tyrosine protein kinase insulin receptor beta-subunit enhance t-cell activation cytoplasmic domain-deleted mutant cd4-p56lck complex occurs cd4-p56lck complex prior cd4-p56lck complex appears antigen-specific signal transduction tyrosine kinase p56lck kinase activity controls atp binding site publisher site pdf cytoplasmic-domain serine phosphorylation phorbol myristate acetate mutant insulin receptor amino-terminal domain license information pmcid 12-amino acid sequence insulin receptor identified receptor-mediated endocytosis protein kinase alters cellular routing anti-peptide antibodies short related sequences retrovirus promoter insertion pmc disclaimer cytoplasmic serine residues insulin-mediated receptor cytoplasmic-domain serine cd4-p56lck complex tcr/cd3 complex ligand-induced internalization optimal antigen stimulation cell surface antigens united states government human thymocyte subpopulations cd8 mediate binding receptor-mediated internalization egf receptor article image mol cell biol search log
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