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Keywords {🔍}

cell, fin, cells, fig, death, ferroptosis, doi, gpx, supplementary, compounds, cil, protein, pubmed, google, scholar, hrs, sqs, lethal, pmc, lethality, article, modulatory, inhibitors, lines, effects, pathway, regulated, lipid, performed, bjelr, target, free, inducers, incubated, shrnas, suppressed, assay, profiling, found, activity, nonapoptotic, added, active, cils, modulators, αtocopherol, effect, gene, biological, glutathione,

Topics {✒️}

supp dataset1 nihms769550-supplement-supp_dataset1 5mm isopropyl β-d-thiogalactoside k-ras-induced cell killing metal-ion-dependent cell death proto-oncogene serine/threonine-protein anti-human α-tubulin antibody y-axis shows fold-enrichment oncogenic-ras-harboring cancer cells anti-human gpx4 antibody hmg-coa-reductase-inhibiting effect label-free proteomic profiling anti-human gpx1 antibody necrostatin-1-dependent cell death anti-human sqs antibody n-terminal his12 tag poly-prep chromatography columns oncogenic-ras synthetic lethality acetonitrile/formic acid gradient rate-limiting step downstream inducing oxidative stress epoxy ring-opening reaction oncogenic-ras-expressing cells housekeeping gene α-tubulin pmc beta search cell-line selectivity improves tumor necrosis factor-alpha dmem high-glucose media representative dose-response curve iron-dependent form caspase-independent cell death synovium-derived stem cells fin56-induced cell death lipophilic antioxidant α−tocopherol pan-pim kinase inhibitors human tumour cells nephrotic tubular death hmg-coa reductase diverse human diseases overexpress oncogenic-ras ferroptosis-inducing compounds reported reactive oxygen species show ‘consistent’ fin56-enhancing identified high-modulatability cils express oncogenic-ras cells tumor-transformed due normal human fibroblasts sigpx4 induced ferroptosis x-axis shows dose-response curve providing mevalonic acid

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