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Keywords {🔍}

cells, sphase, cell, arrest, cancer, aspartate, dna, deprivation, cycle, mdamb, krasdriven, chk, pmc, doi, pubmed, google, scholar, article, calu, biosynthesis, data, glutamine, free, nucleotide, synthesis, mcf, fig, medium, aoa, times, experiments, glutamate, αkg, deoxynucleosides, pathway, shown, repeated, purine, bjhtert, ppat, plated, flow, acid, pyrimidine, response, atr, lack, kras, obtained, control,

Topics {✒️}

anti-rabbit hrp-conjugated igg ataxia telangiectasia-mutated kras-driven mda-mb-231 breast 1μci/ml [3h]thymine deoxyribose k-ras mutant cells experimental procedures cells kras-driven cancers bypass kras-driven cancer calls aoa-induced s-phase arrest chk1-mediated s-phase arrest kras-driven cancer cells kras-regulated metabolic pathway s-phase sensitizes cells single-stranded dna caused s-phase arrested mda-mb-231 kras-driven mda-mb-231 phosphoribosyl pyrophosphate amidotransferase pmc beta search generating cytosolic acetyl-coa s-phase arrest caused atr-chk1 stress pathway unreplicated single-stranded dna single-stranded dna stimulates cancerous bj-htert fibroblasts s-phase arrest induced ataxia telangiectasia inducing s-phase arrest sufficient raw material pmc copyright notice measuring dna content/cell mda-mb-231 cells deprived s-phase arrest observed 5-phosphoribosyl-α-pyrophosphate high-dose rapamycin occur yielding α-ketoglutarate s-phase dna content [3h]thymine deoxyribose supplementary materials included kras-driven cancers tca cycle-derived citrate s-phase-arrested cells bj-htert cells suggests bj-htert cells arrested mda-mb-231 cells arrested de novo purine unreplicated dna caused transaminase inhibitor aoa q-deprived medium single-stranded dna [3h]thymidine deoxyribose

Questions {❓}

• (2014) Drugging the undruggable RAS: Mission possible?
• (2015) You Down With ETC?

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