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Title[redir]:
The Antitumor Effect of Gekko Sulfated Glycopeptide by Inhibiting bFGF-Induced Lymphangiogenesis - PMC
Description:
Objective. To study the antilymphangiogenesis effect of Gekko Sulfated Glycopeptide (GSPP) on human lymphatic endothelial cells (hLECs). Methods. MTS was conducted to confirm the antiproliferation effect of GSPP on hLECs; flow cytometry was employed ...
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Keywords {🔍}
gspp, bfgf, doi, hlecs, tumor, cell, cells, lymphangiogenesis, migration, google, scholar, growth, µgml, pubmed, proliferation, group, cancer, ngml, control, effect, bfgfinduced, lymphatic, mice, metastasis, erk, significantly, formation, inhibited, tumors, inhibiting, study, figure, experiment, perk, endothelial, assay, results, angiogenesis, showed, incubated, pmc, gekko, cycle, tube, treatment, vivo, vitro, width, antitumor, factor,
Topics {✒️}
bfgf-heparin-fgfr terpolymers forming 200 mg/kg/day gspp-treated groups bfgf-heparin-fgfr terpolymers structure bfgf-induced p-erk significantly abrogate bfgf-induced proliferation recombinant human fgf-basic extracellular signal-regulated kinase1/2 pmc beta search tumor-induced lymphangiogenesis played bfgf-induced p-erk peroxidase-conjugated secondary antibodies effective bfgf-targeted inhibitor p-erk protein levels p-erk protein expressions inhibiting bfgf-induced angiogenesis inhibiting bfgf-induced lymphangiogenesis tumor-induced lymphangiogenesis plays vegf-c-induced angiogenesis lymph node lymphangiogenesis—impact inhibiting bfgf-inducing lymphangiogenesis p-erk protein expression ya-nan man 2 low affinity receptor 200 mg/kg/day carcinoma animal model vessel cell proliferation p-erk expression level gspp significantly inhibited heparin active site publisher site pdf gspp-treated groups decreased endothelial cell proliferation primary cell culture bfgf significantly increased gekko sulfated glycopeptide bfgf significantly upregulated ht-29 tumor blocks bfgf-induced lymphangiogenesis gekko sulfated polysaccharide serum-free medium bfgf-induced phosphorylation serum-free ebm-2 license information pmcid cell cycle detection cell cycle distribution akt signaling pathways nude mice models colon carcinoma bfgf 10 ng/ml inhibit cell proliferation
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- Lymphangiogenesis and tumor metastasis: myth or reality?
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