NCBI . NLM . NIH . GOV {
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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC4835968/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC4835968/. The analysis below is for the second page.
Title[redir]:
AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA - PMC
Description:
Lipids stored in lipid droplets are hydrolyzed via either cytosolic lipases or a selective form of macroautophagy known as lipophagy. We recently demonstrated that chaperone-mediated autophagy (CMA) is required for the initiation of lipolysis by ...
Title[redir]:
AMPK-dependent phosphorylation of lipid droplet protein PLIN2 triggers its degradation by CMA - PMC
Description:
Lipids stored in lipid droplets are hydrolyzed via either cytosolic lipases or a selective form of macroautophagy known as lipophagy. We recently demonstrated that chaperone-mediated autophagy (CMA) is required for the initiation of lipolysis by ...
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Keywords {🔍}
plin, ampk, cma, cells, phosphorylation, degradation, cell, pmid, doi, lipid, protein, proteins, pubmed, google, scholar, pmc, autophagy, lipolysis, hspa, httpdxdoiorg, fig, levels, total, article, kinase, free, cuervo, chaperonemediated, treated, inhibitor, cytosolic, control, phosphorylated, ctr, nlm, observed, lysosomal, plins, mice, lysates, pplin, reduction, ncbi, selective, required, lysosomes, phostag, relative, studies, liver,
Topics {✒️}
amp-activated protein kinase deficient chaperone-mediated autophagy chaperone-mediated autophagy depends cma chaperone hspa8/hsc70 chaperone-mediated autophagy map2k1/mek1-map2k2/mek2 l2a knockout pmc beta search cancer-specific ubiquitin ligase ampk-mediated phosphorylation event anti- hspa8/hsc70 phos-tag gel electrophoresis anti-k48-specific ubiquitin src/src tyrosine kinase peroxidase-conjugated secondary antibodies anti-actb/β−actin catalytic subunits prkaa1/α1 cma selectively degrades changing ol-loaded cells anti-p-prkaa/ampkα publisher site pdf pathogen-free conditions l2a ko mice lipid-binding plin proteins fatty acid oxidation membrane protein 2a dynamic protein complexes ol-free medium 06 mm oleate conjugated increased lipid oxidation cytosolic lipase pnpla2/atgl activated ampk hspa8/hsc70 license information pmcid ampk-dependent plin2 phosphorylation pan-tyrosine kinase anti-prkaa/ampkα total protein levels actb/β-actin autophagy effector proteins amino acid sequence 19 phos-tag page phosphate-buffered saline nih3t3 mouse fibroblasts secondary antibody conjugated lysosomal protein degradation phos-tag electrophoresis cell signaling technology mouse embryonic fibroblasts selectively removing plins
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