
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity - PMC
Description:
Emerging single-cell epigenomic methods are being developed with the exciting potential to transform our knowledge of gene regulation. Here we review available techniques and future possibilities, arguing that the full potential of single-cell ...
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Keywords {🔍}
doi, singlecell, cell, pubmed, google, scholar, dna, cells, sequencing, pmc, article, free, epigenetic, single, chromatin, methods, methylation, bisulfite, hmc, nat, stem, modifications, nature, genome, information, parallel, development, heterogeneity, gene, studies, genomewide, cancer, epigenomic, analysis, rnaseq, expression, histone, embryonic, mapping, nucleosome, future, transcriptional, technologies, transcription, performed, reveals, understanding, accessibility, bsseq, approaches,
Topics {✒️}
fluorescence-activated cell sorting tet-assisted bisulfite sequencing undergone micrococcal nuclease polymerase chain reaction genome-wide nucleosome occupancy single-cell multi-omic technologies competing interests single-cell rna-seq data employing single-cell multi-omics single-molecule real-time sequencing high-throughput single-cell labeling single-cell methylome landscapes single-tube reaction immediately single-cell atac-seq method triple-negative breast cancers locus-specific bisulfite pcr single-cell multi-omics scm&t-seq single-cell transcriptome profiling single-cell bs-seq complement single-cell transcriptome single-cell epigenomics techniques cell-type-specific epigenetic marks single-cell analysis reveals post-bisulfite adaptor tagging multiplex single-cell profiling single-cell data arise single-cell rna sequencing single-cell mass cytometry single-cell sequencing technologies generating single-cell libraries single-cell epigenomic approaches single-cell bisulfite conversion single-molecule sequencing technologies single-cell rna-seq [38] single-cell rna-seq post-bisulfite adapter-tagging single-cell sequencing back combined single-cell technologies single-cell epigenomics studies ipsc reprogramming microcococal nuclease digestion single-cell dna sequencing preparing adapter-tagged libraries pmc beta search provide cutting-edge tools bs-seq determines 5hmc nucleosome occupancy single-cell cancer genomics single-cell epigenomic studies
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- What are the earnings of https://doi.org/10.1016/j.cell.2013.04.002?
- https://scholar.google.com/scholar_lookup?journal=Cell&title=Genome-wide%20analysis%20reveals%20TET-%20and%20TDG-dependent%205-methylcytosine%20oxidation%20dynamics&author=L%20Shen&author=H%20Wu&author=D%20Diep&author=S%20Yamaguchi&author=AC%20D'Alessio&volume=153&publication_year=2013&pages=692-706&pmid=23602152&doi=10.1016/j.cell.2013.04.002&'s revenue stream
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- What's the profit of https://scholar.google.com/scholar_lookup?journal=Cell&title=Genome-wide%20profiling%20of%205-formylcytosine%20reveals%20its%20roles%20in%20epigenetic%20priming&author=C-X%20Song&author=KE%20Szulwach&author=Q%20Dai&author=Y%20Fu&author=S-Q%20Mao&volume=153&publication_year=2013&pages=678-91&pmid=23602153&doi=10.1016/j.cell.2013.04.001&?
- Get to know what's the income of https://doi.org/10.1038/nrg3354
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- How much income does https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Genet&title=Chromatin%20structure%20and%20the%20inheritance%20of%20epigenetic%20information&author=R%20Margueron&author=D%20Reinberg&volume=11&publication_year=2010&pages=285-96&pmid=20300089&doi=10.1038/nrg2752& have?
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- What's the financial gain of https://scholar.google.com/scholar_lookup?journal=Science&title=Massively%20parallel%20single-cell%20RNA-Seq%20for%20marker-free%20decomposition%20of%20tissues%20into%20cell%20types&author=DA%20Jaitin&author=E%20Kenigsberg&author=H%20Keren-Shaul&author=N%20Elefant&author=F%20Paul&volume=343&publication_year=2014&pages=776-9&pmid=24531970&doi=10.1126/science.1247651&?
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- Profit of https://doi.org/10.1016/j.stem.2015.07.013
- How much income is https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=Single-cell%20RNA-seq%20with%20waterfall%20reveals%20molecular%20cascades%20underlying%20adult%20neurogenesis&author=J%20Shin&author=DA%20Berg&author=Y%20Zhu&author=JY%20Shin&author=J%20Song&volume=17&publication_year=2015&pages=360-72&pmid=26299571&doi=10.1016/j.stem.2015.07.013& earning monthly?
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- What are the total earnings of https://doi.org/10.1016/j.stem.2014.05.008?
- What's the financial outcome of https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=Reprogramming%20the%20methylome.%20Erasing%20memory%20and%20creating%20diversity&author=HJ%20Lee&author=TA%20Hore&author=W%20Reik&volume=14&publication_year=2014&pages=710-9&pmid=24905162&doi=10.1016/j.stem.2014.05.008&?
- Check the income stats for https://doi.org/10.1038/nbt.3209
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Nat%20Biotechnol&title=High-throughput%20spatial%20mapping%20of%20single-cell%20RNA-seq%20data%20to%20tissue%20of%20origin&author=K%20Achim&author=JB%20Pettit&author=LR%20Saraiva&author=D%20Gavriouchkina&author=T%20Larsson&volume=33&publication_year=2015&pages=503-9&pmid=25867922&doi=10.1038/nbt.3209& bring in?
- Check the income stats for https://doi.org/10.1016/j.stem.2015.01.015
- How much does https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=A%20continuous%20molecular%20roadmap%20to%20iPSC%20reprogramming%20through%20progression%20analysis%20of%20single-cell%20mass%20cytometry&author=ER%20Zunder&author=E%20Lujan&author=Y%20Goltsev&author=M%20Wernig&author=GP%20Nolan&volume=16&publication_year=2015&pages=323-37&pmid=25748935&doi=10.1016/j.stem.2015.01.015& earn?
- Learn about the earnings of https://doi.org/10.1016/j.stem.2014.11.005
- How much does https://scholar.google.com/scholar_lookup?journal=Cell%20Stem%20Cell&title=Single-cell%20transcriptome%20analysis%20reveals%20dynamic%20changes%20in%20lncRNA%20expression%20during%20reprogramming&author=DH%20Kim&author=GK%20Marinov&author=S%20Pepke&author=ZS%20Singer&author=P%20He&volume=16&publication_year=2015&pages=88-101&pmid=25575081&doi=10.1016/j.stem.2014.11.005& pull in?
- How much profit does https://doi.org/10.1016/j.cell.2012.08.023 make?
- How much does https://scholar.google.com/scholar_lookup?journal=Cell&title=Single-cell%20expression%20analyses%20during%20cellular%20reprogramming%20reveal%20an%20early%20stochastic%20and%20a%20late%20hierarchic%20phase&author=Y%20Buganim&author=DA%20Faddah&author=AW%20Cheng&author=E%20Itskovich&author=S%20Markoulaki&volume=150&publication_year=2012&pages=1209-22&pmid=22980981&doi=10.1016/j.cell.2012.08.023& generate monthly?
- What is the monthly revenue of https://doi.org/10.1038/nature12749?
- How much profit does https://scholar.google.com/scholar_lookup?journal=Nature&title=Chromatin%20dynamics%20during%20cellular%20reprogramming&author=E%20Apostolou&author=K%20Hochedlinger&volume=502&publication_year=2013&pages=462-71&pmid=24153299&doi=10.1038/nature12749& make?
- How much does https://doi.org/10.15252/embj.201490649 pull in?
- Monthly income for https://scholar.google.com/scholar_lookup?journal=EMBO%20J&title=Reprogramming%20of%20cell%20fate:%20epigenetic%20memory%20and%20the%20erasure%20of%20memories%20past&author=B%20Nashun&author=PW%20Hill&author=P%20Hajkova&volume=34&publication_year=2015&pages=1296-308&pmid=25820261&doi=10.15252/embj.201490649&
- Profit of https://doi.org/10.1038/nm.3915
- What's https://scholar.google.com/scholar_lookup?journal=Nat%20Med&title=Toward%20understanding%20and%20exploiting%20tumor%20heterogeneity&author=AA%20Alizadeh&author=V%20Aranda&author=A%20Bardelli&author=C%20Blanpain&author=C%20Bock&volume=21&publication_year=2015&pages=846-53&pmid=26248267&doi=10.1038/nm.3915&'s gross income?
- What's the income generated by https://doi.org/10.1101/gr.191098.115 each month?
- Discover the revenue of https://scholar.google.com/scholar_lookup?journal=Genome%20Res&title=The%20first%20five%20years%20of%20single-cell%20cancer%20genomics%20and%20beyond&author=NE%20Navin&volume=25&publication_year=2015&pages=1499-507&pmid=26430160&doi=10.1101/gr.191098.115&
- Revenue of https://doi.org/10.1158/2159-8290.CD-13-0879
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=Cancer%20Discov&title=EGFR%20variant%20heterogeneity%20in%20glioblastoma%20resolved%20through%20single-nucleus%20sequencing&author=JM%20Francis&author=C-Z%20Zhang&author=CL%20Maire&author=J%20Jung&author=VE%20Manzo&volume=4&publication_year=2014&pages=956-71&pmid=24893890&doi=10.1158/2159-8290.CD-13-0879&?
- How much does https://doi.org/10.1126/science.1254257 bring in each month?
- https://scholar.google.com/scholar_lookup?journal=Science&title=Single-cell%20RNA-seq%20highlights%20intratumoral%20heterogeneity%20in%20primary%20glioblastoma&author=AP%20Patel&author=I%20Tirosh&author=JJ%20Trombetta&author=AK%20Shalek&author=SM%20Gillespie&volume=344&publication_year=2014&pages=1396-401&pmid=24925914&doi=10.1126/science.1254257&'s total income per month
- How much profit is https://doi.org/10.1038/nature15260 making per month?
- https://scholar.google.com/scholar_lookup?journal=Nature&title=Single-cell%20analysis%20reveals%20a%20stem-cell%20program%20in%20human%20metastatic%20breast%20cancer%20cells&author=DA%20Lawson&author=NR%20Bhakta&author=K%20Kessenbrock&author=KD%20Prummel&author=Y%20Yu&volume=526&publication_year=2015&pages=131-5&pmid=26416748&doi=10.1038/nature15260&'s financial summary
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- Check the income stats for https://scholar.google.com/scholar_lookup?journal=Nat%20Biotechnol&title=Single-cell%20dissection%20of%20transcriptional%20heterogeneity%20in%20human%20colon%20tumors&author=P%20Dalerba&author=T%20Kalisky&author=D%20Sahoo&author=PS%20Rajendran&author=ME%20Rothenberg&volume=29&publication_year=2011&pages=1120-7&pmid=22081019&doi=10.1038/nbt.2038&
- How much does https://doi.org/10.1038/nrc3130 generate monthly?
- What are the earnings of https://scholar.google.com/scholar_lookup?journal=Nat%20Rev%20Cancer&title=A%20decade%20of%20exploring%20the%20cancer%20epigenome%E2%80%94biological%20and%20translational%20implications&author=SB%20Baylin&author=PA%20Jones&volume=11&publication_year=2011&pages=726-34&pmid=21941284&doi=10.1038/nrc3130&?
- https://doi.org/10.1038/ncomms6899's revenue stream
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Nat%20Commun&title=Methylome%20sequencing%20in%20triple-negative%20breast%20cancer%20reveals%20distinct%20methylation%20clusters%20with%20prognostic%20value&author=C%20Stirzaker&author=E%20Zotenko&author=JZ%20Song&author=W%20Qu&author=SS%20Nair&volume=6&publication_year=2015&pages=5899&pmid=25641231&doi=10.1038/ncomms6899&
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