
NCBI . NLM . NIH . GOV {
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Title[redir]:
Glutamine drives glutathione synthesis and contributes to radiation sensitivity of A549 and H460 lung cancer cell lines - PMC
Description:
Increased glutamine uptake is known to drive cancer cell proliferation, making tumor cells glutamine-dependent. Glutamine provides additional carbon and nitrogen sources for cell growth. The first step in glutamine utilization is its conversion to ...
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Keywords {🔍}
glutathione, cell, doi, glutamine, cells, glutamate, google, scholar, bptes, pubmed, media, figure, cancer, synthesis, lung, lines, tumor, glutaminefree, medium, gls, excretion, time, complete, pmc, radiation, hrs, treatment, mrc, article, culturing, free, proliferation, compared, utilization, significant, excreted, viability, glutaminederived, experiments, production, shown, uptake, results, cglutamine, inhibition, culture, acid, intracellular, hours, metabolites,
Topics {✒️}
gov/docs/misc/common_files/cell_list lc-ms/ms mass spectrometry-based metabolomics faxitron x-ray corp stable isotope-labeled [13c5]-glutamine reduce multi-drug resistance de andrade-lima lc stable isotope-enriched metabolites glutamine-free media supplemented post-hoc comparisons employed glutamine-free medium supplemented pmc beta search temozolomide-resistant glioma cells small-cell lung cancer related gamma-glutamyl compounds ethyl sulfide ethyl sulfide 3 targeted mass spectrometry mass spectrometry analyses cell-free medium control glutamine-free complete media lc-ms quantitation gssg/gsh redox potential γ-glutamyl-cysteine ligase isotope-labeled glutamine experiment glutamine-free media compared glutamine-free media cultures glutamine-free medium compared prevents bptes-induced cytotoxicity [13c5]-glutamine-supplemented media biochim biophys acta platinum-based combination therapies supplementary materials included authors read slower growing a549 mass spectrom rev sensitizes cervical cancer mass spectrometry colony formation showed reduced cell proliferation standard incubation conditions glutamine-free media specific ion transitions glutamine-free medium tumor cell lines cancer biol ther combined standard errors liberate large amounts cell lines synthesize publisher site pdf
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- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi