
NCBI . NLM . NIH . GOV {
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Title[redir]:
A Protective Role for Androgen Receptor in Clear Cell Renal Cell Carcinoma Based on Mining TCGA Data - PMC
Description:
Androgen receptor (AR) is expressed in normal murine and human kidneys of both genders, but its physiologic role is uncertain. Several studies showed loss of AR in renal cell carcinoma (RCC) in conjunction with increasing clinical stage and ...
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Keywords {π}
expression, ccrcc, genes, rcc, prcc, cancer, survival, doi, pubmed, google, scholar, signaling, cell, data, chrcc, patients, androgen, renal, analysis, fig, mrna, protein, gene, role, pathways, pmc, subtypes, cases, carcinoma, correlated, methylation, table, pathway, receptor, article, males, females, arassociated, positively, xlsx, tcga, found, identified, kidney, higher, negatively, free, enriched, circadian, common,
Topics {βοΈ}
pmc beta search estrogen receptor-negative tumors renal cell carcinoma methods ethics statement estrogen receptor-positive tumors data availability statement supporting information files generation anti-androgen therapies reached similar conclusions tissue slice grafts androgen receptor-mediated regulation membrane-anchored kinase transcription factor activity publisher site pdf clear cell [ccrcc] high dose tamoxifen data availability statements higher testosterone levels cell receptor signaling similar transcriptional program license information pmcid multiple molecular subtypes showed negative correlations ar suppresses malignancy ar surviving longer cox regression testa funding statement matching clinical information tumor promoting role renal homeostatic functions ar-correlated gene expression hormone receptor immunoreactivity proteins critically involved high expression predicted normal human kidney phase ii trial coagulation factor vii kaplan-meier curve post-transcriptional processing highly androgen-responsive [6 androgen receptor protein androgen receptor mrna hormone-related tumors androgen receptor cistromes androgen receptor immunohistochemistry androgen receptor-positive average linkage clustering endosomal membrane cycling transcriptome-wide signatures understanding pathologic variants
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- Stone L (2014) Kidney cancer: Androgen receptorβa new target in renal cell carcinoma?
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