
NCBI . NLM . NIH . GOV {
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Title[redir]:
Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors - PMC
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Keywords {🔍}
doi, cell, cells, death, gpx, figure, mice, pubmed, google, scholar, erythroid, necroptosis, ros, rip, caspase, gpxδ, lipid, pmc, data, article, deletion, free, analysis, blood, peroxidation, necrosis, increased, bone, levels, ferroptosis, marrow, anemia, signaling, vitamin, performed, peripheral, glutathione, activation, red, loss, spleen, number, nature, accumulation, role, erythrocytes, inhibitor, hours, apoptosis, tnfr,
Topics {✒️}
o-dianisidine–positive erythroid colonies iv biotinyl-n-hydroxysuccinimide ester fluorophore-conjugated antibodies anti-ter119 fluorescence-activated cell-sorting buffer gpx4-deficient cd71+/ter119+ cells proliferative cd71+/ter119+ erythroblasts tamoxifen-inducible rosa26-creert2/gpx4f/ phosphate-buffered saline vitro–cultured progenitor cells anti–double-stranded dna peripheral cd71+/ter119+ cells favoring jnk1-dependent degradation ligand-dependent cre recombinases mx1-cre transgenic mice32 peripheral cd71+/ter119+ reticulocytes pmc beta search bone marrow-derived progenitors biotin-labeled glutathione ethylester vitro–differentiated erythroid cells long-term jnk1 activation gpx4δ/rip3−/− compound mutants pi+ cd71+/ter119+ cells zvad/taki/tnf-α treatment gpx4δ/rip3−/− double mutants mixed-lineage kinase domain blood web site tak1 inhibitor 5z-7-oxozeaenol cell type–dependent manner cell type–specific difference aif-mediated cell death tnf-α–induced necrosis tumor necrosis factor pi+cd71+ gpx4δ cells gpx4-deficient erythroid cells human recombinant tnf-α anti-phospho-histone h2a anti-cd95l neutralizing antibody enzyme-linked immunosorbent assays gpx4-deficient cell death generate mx1-cre/gpx4f/ page charge payment undergoing rip3-dependent necroptosis suppresses rip3-dependent necroptosis pan-caspase inhibitor zvad rip3−/−/rosa26-creert2/gpx4f/ alpha diagnostic international active-site cysteine biotin-labeling experiments small inhibitor fer-1 discussion erythrocytes
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