NCBI . NLM . NIH . GOV {
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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC4640932/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC4640932/. The analysis below is for the second page.
Title[redir]:
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells - PMC
Description:
Historically, N6-methyladenosine (m6A) has been identified as the most abundant internal modification of messenger RNA (mRNA) in eukaryotes 1. Its mammalian function remained unknown until recently, when it was reported that thousands of mammalian ...
Title[redir]:
N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells - PMC
Description:
Historically, N6-methyladenosine (m6A) has been identified as the most abundant internal modification of messenger RNA (mRNA) in eukaryotes 1. Its mammalian function remained unknown until recently, when it was reported that thousands of mammalian ...
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Keywords {🔍}
mettl, cells, rna, fig, hur, doi, supplementary, analysis, control, binding, methylation, mescs, genes, pmc, levels, scramble, scholar, pubmed, google, targets, article, stability, cell, developmental, protein, showed, regulators, free, proteins, expression, igfbp, increased, versus, panel, enrichment, gene, showing, modification, mrna, observed, mesc, shrna, left, sites, mammalian, probes, scr, shm, pouf, transcripts,
Topics {✒️}
oct4-centered protein-protein interaction hur-microrna pathway functions s-adenosyl-l-methionine conducted 35s-pulse labeling macs peak-calling software rna-binding protein hur rrna-free mrnas extracted sex-specific splicing factor growth factor-ii expression org/gsea/doc/gseauserguideframe rna-induced silencing complex pmc beta search previous clip-seq study21 rna probe exhibiting hur binding site gene-set enrichment analysis rrna-free poly increased hur binding nat cell biol decreased m6a levels molecular mechanisms regulated increased rna levels showed increased expression mettl targets showed hur binding motif kd cells differ increased m6a levels high-throughput sequencing identifying binding sites genome-wide search relative rna levels multiple cellular mechanisms cumulative transcript abundance ontario graduate scholarship ago2 binding sites blocks hur binding ago2-bound mettl3/14 targets mettl kd cells supplementary materials included embryonic stem cells dna-free adomet-binding subunit kd cells relative publisher site pdf m6a rna methylation predicted computationally based high kd efficiency rna-binding proteins detect m6a sites measured m6a levels
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