
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Chaperone-mediated autophagy prevents apoptosis by degrading BBC3/PUMA - PMC
Description:
Autophagy is a potentially inimical pathway and together with apoptosis, may be activated by similar stress stimuli that can lead to cell death. The molecular cues that dictate the cell fate choice between autophagy and apoptosis remain largely ...
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Keywords {🔍}
bbc, cells, fig, tnf, cma, cell, protein, ser, pmid, pubmed, google, scholar, doi, apoptosis, httpdxdoiorg, phosphorylation, levels, ikbkb, degradation, pmc, hct, article, death, wildtype, bbcsa, autophagy, lampa, hspa, free, treatment, lysosomal, stabilization, induction, exposure, chx, depletion, response, data, chaperonemediated, apoptotic, shrna, proteins, transcriptional, activation, stress, inhibitor, role, accumulation, bbcsd, min,
Topics {✒️}
plv-h1-ef1α-puromycin lentiviral vectors tumor necrosis factor chuk/ikkα 6 mg/ml g418 selection cycloheximide-sensitive inhibitor pmc beta search dox-induced cell death tnf-α-induced apoptosis ectopically expressed wild-type 20 μg/ml propidium iodide proapoptotic protein bbc3/puma anxa5/annexin v-fitc cma-depleted cells prompted cma blockage-induced cytotoxicity fluorescent-conjugated secondary antibodies anti-bbc3 antibody showing cytokine/growth factor withdrawal wild-type bbc3 protein ikbkb-mediated ser10 phosphorylation pser10-bbc3 protein levels undergo post-translational modification phospho-mimetic mutant s10d bbc3-dependent cell death wild-type hct116 cells stress type-dependent manner major kinase responsible tumor cell lines nfkb1/nf-κb ikbkb-mediated bbc3 phosphorylation cytokine withdrawal-induced apoptosis lentivirus-mediated shrna tp53-mutant cancer cells blocking cma-mediated degradation tnf-mediated bbc3 phosphorylation bax-induced autophagy contributes induced cdkn1a/p21 human bbc3-α cma-mediated bbc3 degradation human gene knockout sensitize tnf-induced apoptosis bcl2l11/bim stress-induced bbc3 accumulation promotes tumor growth mutant α-synuclein tnf-mediated bbc3 induction impaired cma-dependent degradation chaperone-mediated autophagy tnf-mediated transcriptional induction human somatic cells membrane protein 2a
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- Financial intake of https://www.nih.gov/
- What's the monthly money flow for https://www.hhs.gov/?
- What's https://www.usa.gov/'s gross income?
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi