
NCBI . NLM . NIH . GOV {
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Title[redir]:
Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts - PMC
Description:
A subset of human hepatocellular carcinomas (HCC) exhibit mutations of β-catenin gene CTNNB1 and overexpress Glutamine synthetase (GS). The CTNNB1-mutated HCC cell line HepG2 is sensitive to glutamine starvation induced in vitro with the ...
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Keywords {🔍}
cells, doi, cris, mso, figure, gln, hepg, tumour, pubmed, google, scholar, cell, hcafw, treatment, glutamine, cancer, hcc, pmc, data, growth, article, xenografts, hepatocellular, mice, serum, expression, liver, free, depletion, carcinoma, treated, mutations, βcatenin, synthetase, ctnnbmutated, activity, performed, analysis, metabolism, min, tardito, ctnnb, amino, protein, tumours, crisantaspase, animals, gene, italy, significant,
Topics {✒️}
sirna-mediated beta-catenin knockdown gs inhibitor methionine-l-sulfoximine pmc beta search cg-prkdcscid il2rgtmwjl/sz anti-β-catenin monoclonal antibody asparaginase-resistant hc-afw1 cells γ-glutamylhydroxamate min−1 μg−1 protein ctnnb1-mutated hcc cells hc-afw1 cell line ctnnb1-mutated hcc xenografts supplementary table s1 ctnbb1-mutated hepg2 cells dl-phosphinothricin activate mtor ctnnb1-mutated hcc models high-temperature reaction coil control ctnnb1-mutated hcc anti-β-catenin sirna hc-afw1 cells suggests wnt/beta-catenin signaling hrp-conjugated anti mouse hc-afw1 xenograft growth bio-rad protein assay glutamine synthetase-positive cells drug-related side-effects β-catenin gene ctnnb1 β-catenin/wnt pathway ctnnb1-mutated model intracellular amino-acid content supplementary figure s1 athymic nude mice human hcc ranges effective anti-tumour drugs primary breast cancer male nude mice bd transduction laboratories advance hrp kit reverse-transcriptase control data availability statements human hepatocellular carcinomas supplementary materials included tissue amino-acid analysis hepg2 cell line publisher site pdf helios-γ spectronic delle loro complicanze references armeanu-ebinger methods cell culture ctnnb1 reproducibly segregate wild type ctnnb1 edta-free
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- How much does https://www.usa.gov/ rake in every month?
Analytics and Tracking {📊}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {📚}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {✉️}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {📦}
- Ncbi