
NCBI . NLM . NIH . GOV {
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Title[redir]:
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung - PMC
Description:
Much of the biology surrounding macrophage functional specificity has arisen through examining inflammation-induced polarizing signals, but this also occurs in homeostasis, requiring tissue-specific environmental triggers that influence macrophage ...
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Keywords {🔍}
axl, macrophages, doi, airway, expression, mice, cells, figure, gas, pubmed, google, scholar, lung, infection, tam, influenza, receptor, apoptotic, pmc, article, mertk, cell, free, receptors, analysis, protein, viral, gmcsf, macrophage, immune, data, mrna, expressed, specific, flow, inflammatory, inflammation, supplementary, powerpoint, peritoneal, bmdms, pic, immunol, signaling, slide, human, levels, clearance, relative, antibody,
Topics {✒️}
ammonium-chloride-potassium lysis buffer granulocyte-macrophage colony-stimulating factor granulocyte/macrophage colony-stimulating factor vitamin-k-dependent proteins related axl-negative m-csf-differentiated bmdms nuclear factor-κb repressor macrophage colony-stimulating factor gm-csf-differentiated bmdms isolated gm-csf-differentiated bmdms analyzed bone marrow-derived macrophages growth arrest-specific gene specific pathogen-free conditions competing interests pmc beta search gm-csf-differentiated bmdms lipopolysaccharide-induced endotoxic shock paraffin-embedded lung sections human monocyte-derived macrophages inhibits tnf-alpha production ca-mobilizing growth factors real-time quantitative pcr m1–m3 represent lysates anti-inflammatory signaling cascades anti-ifnar antibody blocked tam triple-knockout mice m-csf-differentiated bmdms mice lacking gm-csf ptdser-expressing influenza virus lps-induced lung injury antigen-presenting cells required gm-csf receptor α anti-ifnar-neutralizing antibody activates anti-inflammatory pathways stat1 phosphorylation-dependent manner triggers ifn-α production growth-potentiating factor growth arrest-specific 6 gas6-axl-related diseases maximal weight loss tam receptors results axl-expressing airway macrophages wild-type mice infected receptor tyrosine kinase primary viral infection murine primary macrophages4 influenza-infected axl−/− mice enhanced pulmonary inflammation license information pmcid advanced glycation endproducts blocks tumor spread
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