
NCBI . NLM . NIH . GOV {
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Title[redir]:
A Limited Role for Antibody in Protective Immunity Induced by rCPAF and CpG Vaccination Against Primary Genital Chlamydia muridarum Challenge - PMC
Description:
Mice deficient in B-cells (μmT mice) were used to evaluate the role of antibody in enhanced chlamydial clearance and reduction of pathology afforded by vaccination with recombinant chlamydial protease-like activity factor (rCPAF). Enhanced, but ...
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Keywords {🔍}
mice, doi, antibody, μmt, chlamydial, genital, vaccinated, infection, cbl, pubmed, google, scholar, cells, mock, animals, rcpafcpg, pathology, pmc, morrison, immunity, muridarum, uterine, chlamydia, role, shown, murthy, article, trachomatis, challenge, clearance, day, free, protective, vaccination, tract, ifnγ, greater, infect, cell, immunol, production, compared, horn, epithelial, fig, immun, iai, primary, cellular, moore,
Topics {✒️}
rcpaf-induced ifn-γ production rcpaf+cpg vaccination/primary genital pmc beta search ifn-γ produced locally minimal ifn-γ production cellular ifn-γ response splenic ifn-γ reponses rcpaf+cpg vaccination induces endogenous ifn-gamma production cooperative ifn-gamma production ifn-gamma-mediated inhibition ni-nta agarose beads human hla-dr4 allele age-matched naïve mice anti-cpaf total ab fc receptor-mediated mechanisms page-purified cpg deoxynucleotides b-cell-deficient mice monoclonal anti-cpaf antibody rcpaf+cpg vaccinated mice antigen-specific cd4+ fc receptor-mediated events rcpaf+cpg vaccinated animals ifn-γ production fc receptor-dependent mechanisms mouse strain-dependent variation greatest cross-sectional diameter rcpaf-induced protective immunity oviduct cross-sectional diameter induced robust systemic cell-deficient mice demonstrate inflammatory cytokine production minimal il-4 production display reduced resistance anti-chlamydial protective immunity rcpaf+cpg vaccination appears significantly reduced compared ifn-γ secretion significantly lower scores chlamydia-induced pathology upper genital tract unrelated antigen hel subunit antigen administered secondary genital infection annu rev microbiol rcpaf+cpg vaccinated reducing ugt pathology accelerated bacterial clearance th1 type cd4+ publisher site pdf
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- https://github.com/ncbi's total income per month
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