
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Phase II DeCOG-Study of Ipilimumab in Pretreated and Treatment-Naïve Patients with Metastatic Uveal Melanoma - PMC
Description:
Up to 50% of patients with uveal melanoma (UM) develop metastatic disease with limited treatment options. The immunomodulating agent ipilimumab has shown an overall survival (OS) benefit in patients with cutaneous metastatic melanoma in two phase ...
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Keywords {🔍}
patients, ipilimumab, melanoma, metastatic, google, scholar, doi, pubmed, treatment, study, phase, uveal, months, pmc, data, survival, rate, median, trial, article, week, aes, free, disease, cancer, clinical, table, pdf, dose, number, alc, pretreated, treatmentnaïve, year, studies, received, tumor, activity, safety, mgkg, response, inhibitor, fig, doses, oncol, advanced, efficacy, criteria, results, death,
Topics {✒️}
c-met/vegfr2 inhibitor cabozantinib skin-related toxic effects—pruritus dana-farber cancer institute pmc beta search histone-deacetylase inhibitor vorinostat regulates t-cell activation weekly docosahexaenoic acid-paclitaxel helsinki/good clinical practice engineered pd-l1 antibody data availability statement immune-related response criteria anti-pd-l1 antibody protocol-specific treatment algorithms protocol-specific treatment guidelines immune-related gastrointestinal aes bristol-myers squibb supporting information files decog-mm-pal11-trial treatment-related death due including immune-related aes um remains ill-defined progression-free survival [google scholar] 12 [google scholar] 18 [google scholar] 24 [google scholar] 31 [google scholar] 38 long-term survival benefit /ii study evaluating phase iii trials drug-related death due data availability statements license information pmcid american joint committee skin cancer units phase ii trial supporting trend checklist evaluated 10mg/kg ipilimumab phase ii study supplementary materials included publisher site pdf anti-pd-1 antibody randomized clinical trial immune-related gastrointestinal spanish melanoma group multicentric randomized trial emerging toxicity profiles mek inhibitor trametinib protocol-specific guidelines immune checkpoint molecule
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