
NCBI . NLM . NIH . GOV {
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Title[redir]:
Myeloid-Derived Suppressor Cells Impair Alveolar Macrophages through PD-1 Receptor Ligation during Pneumocystis Pneumonia - PMC
Description:
Myeloid-derived suppressor cells (MDSCs) were recently found to accumulate in the lungs during Pneumocystis pneumonia (PcP). Adoptive transfer of these cells caused lung damage in recipient mice, suggesting that MDSC accumulation is a mechanism of ...
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Keywords {🔍}
doi, ams, cells, mdscs, expression, pubmed, google, scholar, incubated, mice, pmc, grbm, article, free, cell, fig, pneumocystis, pcp, isolated, control, antibody, levels, immunol, macrophages, uninfected, pdl, dna, fold, pdpdl, phagocytosis, beads, infection, gene, programmed, death, signaling, pathway, zymosan, zhang, downregulation, lee, increased, antipdl, immune, realtime, data, alveolar, activity, pneumocystisinfected, compared,
Topics {✒️}
services/applications/epigenetics-noncoding-rna-research/chromatin-remodeling/chromatin-immunoprecipitation-chip/chip-analysis granulocyte-macrophage colony-stimulating factor tuberculosis-specific ifn-γ-producing pd-1/pd-l1 signaling pathway anti-pd-l1 antibody abolished anti-pd-l1 antibody abrogated biotin-conjugated anti-cd11c antibody vitro gm-csf/il-4-induced differentiation anti-pd-l1 antibody reduced pd-1/pd-l1 signaling reduced anti-pd-l1 antibodies prevents pd-1/pd-l1 signaling directly biotin-anti-mouse cd11c antibody anti-biotin magnetic microbeads block pd-1/pd-l1 signaling anti-pd-l1 versus levels feed-forward transcriptional circuit itim motif-carrying immunoreceptor pd-1/pd-l1 pathway pd-l1/pd-1 pathway myeloid-derived suppressor cells anti-gr-1 antibody-conjugated 1 real-time rt-pcr real-time rt-pcr intronic single-nucleotide polymorphism anti-pd-l1 antibody pd-1/pd-l1 signaling interferon-sensitive response element ifn-alpha-induced upregulation pmc beta search composite ap-1/ets motif anti-mouse pd-l1 pd-1/pd-l1 ligation tumor antigen-specific cd8+ sustains virus-specific cd8+ protein a-agarose beads perform chromatin immunoprecipitation high-permeability pulmonary edema activate anti-tumor immunity cross-link histone proteins melanoma antigen-specific ctl anti-pd-l1 antibodies cd8+ t-cell exhaustion pd-1 receptor-deficient mice programmed death 1-mediated fluorescein-conjugated zymosan beads induce pd-l1 expression fluorescent anti-mouse antibodies interferon gamma responsiveness enhancing siv-specific immunity
Questions {❓}
- Why does the autoantibody against granulocyte-macrophage colony-stimulating factor cause lesions only in the lung?
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