
NCBI . NLM . NIH . GOV {
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Title[redir]:
Liver X receptor agonist treatment attenuates cardiac dysfunction in type 2 diabetic db/db mice - PMC
Description:
Liver X receptor (LXR) plays a critical regulatory role in metabolism and inflammation, and has been demonstrated to be involved in cardiovascular physiology/pathology. In the present study, we investigated the effect of GW3965, a potent LXR ...
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Keywords {🔍}
doi, dbdb, mice, lxr, diabetic, pubmed, google, scholar, myocardial, glucose, cardiac, figure, stress, insulin, agonist, activation, group, pmc, tissue, expression, dcm, liver, resistance, left, heart, protein, article, ventricular, free, receptor, treatment, apoptosis, determined, dysfunction, results, lxrα, type, mapk, diabetes, nuclear, mouse, cardiomyopathy, model, analysis, fibrosis, akt, myocardium, inflammatory, diabetesinduced, oxidative,
Topics {✒️}
enzyme-linked immunosorbent assay rabbit anti-glyceraldehyde-3-phosphate dehydrogenase nuclear factor kappa-light-chain-enhancer left ventricular pressure tumor necrosis factor-α reactive oxygen species mitogen-activated protein kinase interleukin 1-beta relative light units left ventricular dysfunction homeostasis model assessment left ventricular function glucose tolerance test lv pressure left ventricle pmc beta search interleukin-1β lvef tc total cholesterol rabbit anti-phospho-p38 mapk mid-ventricular short axis serum triglyceride liquid nitrogen 12 hour light-dark cycle reactive nitrative stress tgf-β1 il-1β content total cholesterol homa-ir index glucose homeostasis il-1β levels lvsp lvedp including tnf-α small-molecular-weight natural product highly reactive onoo mitigates diabetes-induced activation improved glucose tolerance activated inos rabbit anti-phospho-jnk phospho-p38 mapk cardiomyocyte-expressed farnesoid-x-receptor diabetes mellitus ventricular tissue il-1β inos gene expression myocardial ischemia/reperfusion injury homa-ir total cross-sectional area inhibited inos expression
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