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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC4226722/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC4226722/. The analysis below is for the second page.
Title[redir]:
IsomiR expression profiles in human lymphoblastoid cell lines exhibit population and gender dependencies - PMC
Description:
For many years it was believed that each mature microRNA (miRNA) existed as a single entity with fixed endpoints and a ‘static’ and unchangeable primary sequence. However, recent evidence suggests that mature miRNAs are more ‘dynamic’ and that each ...
Title[redir]:
IsomiR expression profiles in human lymphoblastoid cell lines exhibit population and gender dependencies - PMC
Description:
For many years it was believed that each mature microRNA (miRNA) existed as a single entity with fixed endpoints and a ‘static’ and unchangeable primary sequence. However, recent evidence suggests that mature miRNAs are more ‘dynamic’ and that each ...
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Keywords {🔍}
isomirs, isomir, mirbase, doi, arm, population, mirna, supp, expression, samples, populations, precursor, reference, mirp, google, scholar, ceu, yri, file, pubmed, pmc, terminus, abundant, fig, groups, expressed, article, identified, gbr, oncotargetsxlsx, xlsx, cell, data, free, mature, targets, fin, tsi, arms, mirnas, ago, differences, reads, replicates, show, datasets, figure, compared, single, rna,
Topics {✒️}
uk/arrayexpress/files/e-geuv-1/analysis_results/ org/web/geuvadis/rnaseq-project ago par-clip data pmc beta search ago par-clip datasets high-throughput sequencing reads argonaute par-clip data find par-clip support pair-wise population comparisons exhibit gender-dependent differences x-axis shows differences pair-wise comparisons ranging supplementary materials oncotarget-05-8790-s001 ago par-clip [google scholar] 3 [google scholar] 26 y-axis shows differences depicts redundant information date examined collections publisher site pdf unchangeable primary sequence bmc res notes pair-wise comparisons mir-143-3p precursor arm mir-1304-3p precursor arm license information pmcid competing financial interests reach statistical significance receive similar levels vertebrate microrna species distribution information separately large primary transcripts pattern-based method mature mirna product lymphoblastoid cell lines microrna binding sites passed quality control sequence-dependent manner multiple mature products supplementary figures future studies involving single mature product highly differentially expressed human genome variation human population separated hairpin precursor mirna deep-sequencing artifact deep sequencing data deep-sequencing data ago silencing complex
Questions {❓}
- Could it be that the mature miRNA product variability that we observe within the span of a precursor arm is due to technical artifacts or random degradation?
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