NCBI . NLM . NIH . GOV {
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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC420348/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC420348/. The analysis below is for the second page.
Title[redir]:
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients - PMC
Description:
Resistance to chemotherapy is a major cause of mortality in advanced cancer patients. In this study, digital karyotyping was used to search for genomic alterations in liver metastases that were clinically resistant to 5-fluorouracil (5-FU). In two ...
Title[redir]:
Digital karyotyping identifies thymidylate synthase amplification as a mechanism of resistance to 5-fluorouracil in metastatic colorectal cancer patients - PMC
Description:
Resistance to chemotherapy is a major cause of mortality in advanced cancer patients. In this study, digital karyotyping was used to search for genomic alterations in liver metastases that were clinically resistant to 5-fluorouracil (5-FU). In two ...
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Custom-built
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Keywords {🔍}
tyms, amplification, patients, cancer, google, scholar, pubmed, gene, doi, resistance, colorectal, metastases, dna, genomic, chromosome, treatment, analysis, treated, survival, cells, genome, fum, genetic, amplified, clin, metastatic, cancers, patient, fig, liver, tumors, tags, pmc, expression, human, tag, obtained, lesions, regions, fish, danenberg, nlm, alterations, days, levels, densities, tumor, bac, genes, oncol,
Topics {✒️}
antibody-conjugated magnetic beads anti-digoxigenin mouse antibody anti-berep4 immunomagnetic beads streptavidin-coated magnetic beads biotinylated anti-avidin antibody quantitative real-time pcr pmc beta search 6′-diamidino-2-phenylindole stain signals bcr/abl fusion gene paraffin-embedded samples publisher site pdf 6′-diamidino-2-phenylindole stain sequence tag densities genomic tag densities higher tag density high-resolution map 96-capillary abi3700 instrument decreased genomic density advanced cancer patients license information pmcid primary colorectal cancer isothiocyanate-conjugated antibodies dihydrofolate reductase gene 5-fu-based therapies christine iacobuzio-donahue online mendelian inheritance provided unique insights approach involves isolation institutional review board accountability act regulations 1 mg/ml collagenase big dye terminators threshold cycle numbers kaplan-meier method single continuous amplicon bitmap views comprised familial adenomatous polyposis proportional hazard model chronic myelogenous leukemia genome databases identified quantitative pcr analyses copy number alterations digoxigenin-labeled signals kaplan-meier analyses adenoma tissue obtained maximal genomic densities bcr/abl gene line element control high tyms protein provide unambiguous information
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