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Keywords {🔍}

doi, αsynuclein, cells, hsc, pubmed, google, scholar, mira, shsyysyn, expression, degradation, lampa, level, autophagy, mimics, cell, pmc, transfection, protein, disease, αsyn, usa, cma, mrna, article, figure, mirna, free, post, aggregation, influence, levels, analysis, microrna, mirnas, control, chaperonemediated, parkinsons, significantly, shsyy, science, utr, western, blot, mirnaa, accumulation, statistical, targeted, study, human,

Topics {✒️}

microrna cluster mir-29a/b-1 expressing wild-type α-synuclein wild-type α-synuclein degradation increased bace1/β-secretase expression variously propagated sh-sy5y-syn real-time rt-pcr method microrna-mediated α-synuclein degradation real-time quantitative pcr wild type α-synuclein long-lasting synaptic plasticity step rt-pct kit expressing human α-synuclein mir-320a mimics transfection mirna-320a mimics transfection mir-320a specifically targeted pmc beta search chaperone-mediated autophagy markers α-synuclein locus triplication recycle long-lived proteins mir-320a mimics concentration sh-sy5y cell line tab sh-sy5y-syn neuro-pathological aggregated proteins impaired α-synuclein degradation rate-limiting lysosomal receptor expressed sh-sy5y-syn expressed sh-sy5y cells α-synuclein protein levels publisher site pdf normal sh-sy5y cells mir-320a mimics mirna-320a mimics mirna-320a targets expressing α-synuclein downregulating lamp-2a leads license information pmcid sh-sy5ycell line mir-320a transfection chaperone-mediated autophagy α-synuclein accumulation α-synuclein accumulation [10 taqman microrna assays α-synuclein aggregates α-synuclein locus mir-320a targeted western blot assay expressed α-synuclein potential therapeutic targets midbrain dopamine neurons α-synuclein degradation

Questions {❓}

• Dysfunction of two lysosome degradation pathways of α-synuclein in Parkinson’s disease: Potential therapeutic targets?
• α-Synuclein fate: Proteasome or autophagy?

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