
NCBI . NLM . NIH . GOV {
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Title[redir]:
Human-Specific Bacterial Pore-Forming Toxins Induce Programmed Necrosis in Erythrocytes - PMC
Description:
A subgroup of the cholesterol-dependent cytolysin (CDC) family of pore-forming toxins (PFTs) has an unusually narrow host range due to a requirement for binding to human CD59 (hCD59), a glycosylphosphatidylinositol (GPI)-linked complement regulatory ...
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Keywords {🔍}
rbc, rbcs, necrosis, programmed, vly, death, fig, rip, ily, pfts, doi, pubmed, google, scholar, bacterial, cell, caspase, formation, growth, mature, human, pcd, pmc, vaginalis, enhanced, cells, fasl, inhibition, induce, figure, tif, hcdspecific, article, eryptosis, intermedius, ply, rfasl, role, free, pft, response, fas, phosphorylation, lipid, hemolysis, igg, binding, ceramide, hcdindependent, nucleated,
Topics {✒️}
induce fas/fasl-dependent death nox/iron-dependent ros production fas/fasl-dependent programmed necrosis nox/iron-dependent ros formation versatile pore-forming toxins 10 µm z-devd-fmk bacterial pore-forming toxins hcd59-specific pft-producing pathogens human-specific bacterial toxins �-tetraacetic acid–acetoxymethyl ester] human-specific pft production fasl-dependent rbc death fasl-dependent programmed necrosis fasl-dependent bystander death anti-phospho-ser/thr nox-dependent ros contribute hcd59-specific bacterial pfts nox/iron-dependent ros pmc beta search hcd59-specific pft-producing fas/fasl-dependent death human-specific bacterial pfts mixed-lineage kinase domain specific methylglyoxal-derived age hcd59-specific pfts produced softly—suicidal erythrocyte death extra-vaginal infection caused dot/western blot assays rip1-dependent cell death hcd59-independent pfts pneumolysin pore-forming toxins lipid raft-dependent signaling fas-specific agonistic mab anti-cdc polyclonal antibody mlkl-dependent programmed necrosis hcd59-independent pft-producing cholesterol-dependent cytolysin produced pft-producing pathogenic bacteria asmase-dependent ceramide formation hcd59-transgenic murine rbcs anti-age polyclonal antibody hcd59-specific pft induction rbc detergent-resistant membranes pab anti-cdc serum nonmetabolizable 2-deoxy-d-glucose specific cellular target tumor necrosis factor dot blots showing induce programmed necrosis anti-caspase-8 mab 12f5
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