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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC4148686/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC4148686/. The analysis below is for the second page.
Title[redir]:
Sequence analysis of mutations and translocations across breast cancer subtypes - PMC
Description:
Breast carcinoma is the leading cause of cancer-related mortality in women worldwide with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone1. This malignancy represents a heterogeneous group of tumours with characteristic ...
Title[redir]:
Sequence analysis of mutations and translocations across breast cancer subtypes - PMC
Description:
Breast carcinoma is the leading cause of cancer-related mortality in women worldwide with an estimated 1.38 million new cases and 458,000 deaths in 2008 alone1. This malignancy represents a heterogeneous group of tumours with characteristic ...
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Keywords {🔍}
doi, mutations, breast, cancer, supplementary, akt, scholar, google, pubmed, nature, figure, gene, fusion, samples, sequencing, mutation, pmc, dna, analysis, magiakt, table, performed, cancers, article, somatic, genomic, rearrangements, genes, data, human, runx, subtypes, copy, cbfb, expression, methods, mutated, science, recurrent, kinase, domain, tumour, magi, free, number, sample, nlm, cases, including, erbb,
Topics {✒️}
core-binding-factor beta subunit chimeric gene cbfb/pebp2b-mhy11 atp-competitive akt inhibitors tables nihms619199-supplement-supplementary_methods__figures_and_tables v-erbb-related gene org/display/cgatools/mutect org/display/cgatools/indelocator org/display/cgatools/home dana-farber/harvard spore uk/genetics/cgp/cosmic/ small-cell lung cancer pmc beta search notch family-gene fusions24 disrupts zinc-finger domains inferred segmental copy-ratios target protein-coding regions org/display/cgatools/mutsig predicted 5′-magi3-akt3-3′ fusion allele-specific copy number protein-altering point mutations magi3-akt3 overexpressing cells magi3-akt3 fusion protein tumor suppressor pten/mmac cbfb-myh11 translocation believed tumour/normal dna pairs magi3-akt3 fusion gene allosteric akt inhibitor magi3-akt3 fusion leads 5′-magi3-akt3-3′ fusion event tumour-specific point mutations dominant negative function21 transcription factor complex combines magi3 lacking characteristic molecular features mass-spectrometric genotyping additional mutation calling analysed genetic material breast cancer genomes dna binding component runx binding domain nih grant ca122099 segmented copy number copy number level 103 tumour-normal pairs wild-type protein cancer-related mortality akt3 protein domains frame fusion gene fusion gene ectopically notch gene families
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