
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Genome-Wide Analysis of miRNA-mRNA Interactions in Marrow Stromal Cells - PMC
Description:
Regulation of hematopoietic stem cell proliferation, lineage commitment, and differentiation in adult vertebrates requires extrinsic signals provided by cells in the marrow microenvironment (ME) located within the bone marrow. Both secreted and ...
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Keywords {π}
cells, doi, pubmed, google, scholar, cell, binding, stromal, mirna, mira, pmc, analysis, marrow, rna, article, endothelial, free, human, stem, hematopoietic, peaks, mirnas, hitsclip, hsa, bone, expression, jag, luciferase, fig, region, data, shown, control, mmp, transfected, peak, putative, performed, agomrna, regulation, sequencing, wnta, assays, information, vegfa, functional, protein, ago, interactions, rnas,
Topics {βοΈ}
hgs_dootheruser=submit&hgs_otherusername=mmpillai&hgs_otherusersessionname=balakrishnan_stem%2dcells Ο-check-mut-mmp-mre vectors bone-marrow haematopoietic-stem-cell niches Ο-check-mut-vegfa-mre vectors Ο-check-mut-wnt5a-mre vectors generate Ο-check-vegfa-mre generate Ο-check-wnt5a-mre generate Ο-check-mmp2-mre mdh-pfk-control viral vectors supp2 nihms606611-supplement-supp2 long-term quiescence geo short-read archive fluorescence-activated cell sorting token=vdknveyqyqaucvk&acc=gse41272 xhoi-noti restriction sites bamhiβecori restriction sites hrp-conjugated secondary antibody Ο-check2-jag1-mutant mre pro-b-cell chemotaxis pmc beta search marrow-derived endothelial cells genome-wide biochemical approaches stable single-cell clones marrow-derived stromal cells positive single-cell clones gov/geo/query/acc unbiased genome-wide datasets genome-wide biochemical technique cxcl12-cxcr4 chemokine signaling sl/sld hematopoietic progenitors unbiased genome-wide views unbiased genome-wide biochemistry studying mirna-mrna interactions hits-clip analysis showed fire-fly luciferase activity bioinformatic seed-pair matching hits-clip datasets due mapping rna-protein interactions single mirna-mrna interactions cross-species sequence conservation uv cross-linked cells ago hits-clip datasets psi-check jag1-mre ago-bound mrna sites wnt/beta-catenin signaling called agom-rna peaks rna-induced silencing complex define mirna-mrna interactions mdh1-pgk-gfp vector [29] stromal-derived factor 1
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