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Keywords {🔍}

cells, cisplatin, btg, cell, expression, lncap, cancer, prostate, gene, pubmed, google, scholar, doi, figure, proliferation, response, nfκb, activity, hours, psa, results, treatment, assay, treated, induced, element, reporter, concentrations, growth, dna, cycle, expressions, pathway, pmc, promoter, shown, vector, human, inhibition, previous, determined, protein, assays, usa, carcinoma, antigen, apoptosis, blocked, study, manner,

Topics {✒️}

long-term biochemical disease-free nf-kappab-responsive gene btg2 human btg2/tis21/pc3 gene ikk/nf-κb signaling plays real-time pcr system cisplatin-mediated growth inhibition site-directed mutagenesis abolished btg2-mediated cyclin d1 ad prostate-specific antigen prostate-specific antigen kinetics btg2 gene p53-dependently p53 wild-type lncap 3h-thymidine incorporation assay h3-thymidine incorporation assay prostate-specific antigen expression antiproliferative p53-dependent component pmc beta search prostate-derived ets factor mock-transfected lncap cells ubiquitin-proteasom system induced estrogen receptor-dependent induction p53-null cancer cells12 pc3/btg/tob family pcmv-iκbαm expression vector prostate cancer-specific survival 5 μg/ml puromycin dihydrochloride mock-knockdown lncap cells unidentified p53-independent pathway p53-wild lncap cells author contributions tissue- specific manner9 psa expression p53-indirectly p53-null pc-3 cells β-galactosidase expression vector p53-independent nfκb pathway prostate specific antigen prostate-specific antigen attenuated salmonella carrying nanoparticle-mediated codelivery human btg2 gene tumor suppressor gene btg/tob family transient overexpression iκbα btg2 mrna levels btg2 reporter vectors androgen receptor activity prostate cancer cell nf-kappab signaling ke-hung tsui 2 subsequent nuclear translocation

Questions {❓}

• Is NF-kappaB a good target for cancer therapy?
• The gene PC3(TIS21/BTG2), prototype member of the PC3/BTG/TOB family: regulator in control of cell growth, differentiation, and DNA repair?

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