NCBI . NLM . NIH . GOV {
}
We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC4058317/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC4058317/. The analysis below is for the second page.
Title[redir]:
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction - PMC
Description:
In a cell-free approach to regenerative therapeutics, transient application of paracrine factors in vivo could be used to alter the behavior and fate of progenitor cells to achieve sustained clinical benefits. Here we show that intramyocardial ...
Title[redir]:
Modified mRNA directs the fate of heart progenitor cells and induces vascular regeneration after myocardial infarction - PMC
Description:
In a cell-free approach to regenerative therapeutics, transient application of paracrine factors in vivo could be used to alter the behavior and fate of progenitor cells to achieve sustained clinical benefits. Here we show that intramyocardial ...
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Custom-built
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Traffic Estimate {📈}
What is the average monthly size of ncbi.nlm.nih.gov audience?
🌠 Phenomenal Traffic: 5M - 10M visitors per month
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How Does Ncbi.nlm.nih.gov Make Money? {💸}
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Keywords {🔍}
vegfa, modrna, doi, cells, myocardial, infarction, fig, epicardial, cell, heart, pubmed, google, scholar, expression, endothelial, cardiac, dna, progenitors, epdcs, fate, pmc, progenitor, supplementary, lineage, differentiation, hearts, kdr, article, control, increased, free, gene, transfection, cre, mice, gfp, adult, days, treatment, vivo, cardiomyocytes, muscle, effect, performed, vascular, injection, vitro, cardiomyocyte, delivery, marker,
Topics {✒️}
rosa26-lox-stop-lox-lacz kdr+/ve-cadherin+ endothelial cells post-natal mammalian heart mantel-cox log-rank test initially ve-cadherin negative resulting epicardium-derived cells fleeting tissue half-lives flurochrome-conjugated primary antibodies endothelial marker ve-cadherin wt1-driven cre alleles induce creert2-mediated recombination pmc beta search adult cardiac-resident msc anti-viral immune responses anti-viral immune responses16 ve-cadherin negative clone post-myocardial infarction hearts cre-activated β-galactosidase genetic cre-loxp assessment wt1-driven marker alleles treatment-blind cell counts mixed c57bl6/cfw background gfp-cre fusion protein dna-mediated gene transfer modrna-mediated gene transfer facs-purified gfp+ cells advanced bioscience resources wnt/beta-catenin pathway wt1-driven gfp marker isl1+ cardiovascular progenitors cre modrna-labeled epdcs tamoxifen free base cell-free approach achieve long-term benefit enhanced long-term survival tamoxifen-independent cre activity endogenous progenitor pool nat biotechnol abstract relative qrt-pcr-measured expression epicardium-derived cells kdr/flk-1 receptor expression specific small-molecule inhibitors wt1-gfp+ cell isolation endogenous cardiovascular progenitors7 license information pmcid double positive cells epicardial progenitor cells vegf-induced adult neovascularization cardiac progenitor markers wt1+ epicardial progenitors
Questions {❓}
- These beneficial effects required VEGF-A signaling through its canonical receptor KDR (also known as VEGFR2), because they were [AU: OK?
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