NCBI . NLM . NIH . GOV {
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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3981172/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC3981172/. The analysis below is for the second page.
Title[redir]:
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway - PMC
Description:
The final step of cytoplasmic mRNA degradation proceeds in either a 5′-3′ direction catalysed by Xrn1 or in a 3′-5′ direction catalysed by the exosome. Dis3/Rrp44, an RNase II family protein, is the catalytic subunit of the exosome. In humans, there ...
Title[redir]:
The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway - PMC
Description:
The final step of cytoplasmic mRNA degradation proceeds in either a 5′-3′ direction catalysed by Xrn1 or in a 3′-5′ direction catalysed by the exosome. Dis3/Rrp44, an RNase II family protein, is the catalytic subunit of the exosome. In humans, there ...
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Keywords {🔍}
disl, degradation, rna, exosome, doi, pubmed, google, scholar, figure, mrna, deletion, pmc, protein, yeast, article, complex, cytoplasmic, free, pombe, dis, proteins, analysis, cerevisiae, supplementary, transcripts, lsmδ, results, substrate, pbodies, gene, parker, cells, decapping, conserved, single, active, sequence, uridylated, strain, data, biol, uridylation, substrates, decay, end, media, xrn, mrnas, stress, reaction,
Topics {✒️}
including grant pest-oe/eqb/la0004/2011 double-stranded rna/dna substrate pmc beta search osmosensing map-kinase pathway n-terminal cr3 region phenol-chloroform isolation method fct post-doctoral fellowship n-terminal pin domain dcp2-rfp labelled p-bodies full-length polyadenylated messages stored inside p-bodies single amino-acid substitution p-body marker dcp2 mrna-binding protein ssd1 mrna steady-state levels yeast mitochondrial degradosome status examination—pase method dcp1–dcp2 decapping complex 5 μg/ml hoechst solution active ribonuclease rrp44/dis3 wild-type protein digested wild-type protein product cells expressing dis3l2-gfp weaker dis3l2-gfp foci wt—wild-type strain n-terminal pin grant fp7-kbbe-2011-1-289326 license information pmcid transcriptional gene silencing rna-bound complex dis3l2δlsm1δ double mutants slower degradation rate lin28-mediated control cerevisiae rrp44/dis3 sequence double-stranded substrate eukaryotic species representing enhanced ratio method pmc disclaimer dis3l2δski2δ double mutants xhoi restriction site 11-nt random sequence phylogenetic analyses proved cerevisiae dis3p/rrp44p sequence bacterial rnase ii single-stranded substrate 2 single invertebrate species mrna degradation pathway pfa6a tap kan active site consensus post-transcriptional modifications
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