NCBI . NLM . NIH . GOV {
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Title[redir]:
Accurate and Robust Prediction of Genetic Relationship from Whole-Genome Sequences - PMC
Description:
Computing the genetic relationship between two humans is important to studies in genetics, genomics, genealogy, and forensics. Relationship algorithms may be sensitive to noise, such as that arising from sequencing errors or imperfect reference ...
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Keywords {🔍}
grab, relationships, relationship, data, individuals, wgs, families, thdegree, ibs, pmc, doi, genetic, degree, unrelated, pubmed, google, scholar, genome, article, sequencing, simulated, ersa, table, analysis, error, free, wholegenome, king, plink, accuracy, figure, iws, number, time, estimation, real, phasing, genotyping, pairs, nlm, reported, set, pedigree, ibd, genomewide, panels, snvs, pcutoff, open, tab,
Topics {✒️}
oligo-based hybridization techniques genome-wide association studies pmc beta search population-based linkage analyses high-density snp data population-based association study common single-nucleotide polymorphisms full-called biallelic snvs high-density genotyping arrays results software validation publisher site pdf discordant 1st-degree relationships accurate predict 1st-degree user-guided selection identifies 1st-degree genome-wide sharing genome-wide mapping ibd algorithms improve population allele frequencies single nucleotide variant genome-wide estimates user-defined threshold genome-wide metrics united states government license information pmcid �low pass” filter passed numerous rounds hardy-weinberg equilibrium variant call format hardy-weinberg equilibria average inherently harder parsing pedigree file influence adult height de bakker pi framingham heart study recent shared ancestry genome variant information genome management system asthma genome scans imperfect reference genomes ped+map file call rate greater linear discriminant analysis �low-pass filtering” passing filtering criteria 5th-degree relations identifying unreported relationships validating reported relationships meiotic crossover points manual verification revealed
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