
NCBI . NLM . NIH . GOV {
}
Title[redir]:
In Utero Exposure to Diesel Exhaust Air Pollution Promotes Adverse Intrauterine Conditions, Resulting in Weight Gain, Altered Blood Pressure, and Increased Susceptibility to Heart Failure in Adult Mice - PMC
Description:
Exposure to fine particulate air pollution (PM2.5) is strongly associated with cardiovascular morbidity and mortality. Exposure to PM2.5 during pregnancy promotes reduced birthweight, and the associated adverse intrauterine conditions may also ...
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Keywords {๐}
exposure, doi, utero, pubmed, google, scholar, mice, adult, pmc, placental, free, weight, article, heart, pressure, figure, exposed, air, susceptibility, increased, pollution, blood, observed, cardiovascular, diesel, failure, effects, body, male, exhaust, vascular, tac, disease, dams, cardiac, area, journal, fetal, evidence, function, promote, cell, oxidative, stress, individual, sham, health, particulate, injury, weeks,
Topics {โ๏ธ}
pro-inflammatory high-density lipoprotein mitochondrial beta-oxidation enzymes pkc{epsilon} gene repression newborn growth-retarded rat diet-induced metabolic syndrome female c57bl/6j mice pmc beta search fetomaternal immune cross-talk lv free wall methods ethics statement bioavailable nitric oxide atherosclerotic plaques induced inhaled particulate matter specific pathogen free baseline ventricular dysfunction short-term inhalation exposure publisher site pdf alters blood pressure prenatal cocaine exposure inhaled diesel exhaust left ventricular mass free radical biology particulate air pollution myocardial gene expression diesel exhaust exposure left ventricle wall primary antibody directed 53 ยตg/m3/hr pm2 inflammatory cell infiltration diesel exhaust exposures promote systemic vascular mild perivascular fibrosis adverse intrauterine conditions adverse intrauterine environment individual cardiomyocyte hypertrophy recent meta-analysis license information pmcid coda o-cuff risk factor clusters mitochondrial oxidative stress normalizes iugr-induced vascular oxidative stress cardiac myocyte hypertrophy glutathione synthesis genes placental insufficiency results long-term exposure systemic vascular function utero de-tac mice citywide air pollution transverse aortic constriction
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