
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Overcoming Current Limitations in Humanized Mouse Research - PMC
Description:
Immunodeficient mice engrafted with human cells and tissues have provided an exciting alternative to in vitro studies with human tissues and nonhuman primates for the study of human immunobiology. A major breakthrough in the early 2000s was the ...
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Keywords {π}
human, mice, doi, cells, google, scholar, pubmed, immune, humanized, pmc, engraftment, development, mouse, model, cell, article, nsg, blood, free, responses, hiv, immunity, innate, system, blt, models, levels, class, immunodeficient, nodscid, approaches, immunol, engrafted, hematopoietic, function, murine, shultz, host, increased, receptor, systems, hsc, observed, mhc, limitations, functional, immunodeficiency, peripheral, leads, infection,
Topics {βοΈ}
hu-pbl-severe combined immunodeficiency /granulocyte-macrophage colony-stimulating factor humanized nod/shi-scid/gammac hu-pbl-scid model system nsg-hla-dr4 tg mice nod/ltsz-scid/scid mice c57bl/6j-scid bg mice nog-hla-dr4 mice engrafted sirpΞ±-cd47 receptor-ligand axis intestinal t-cell reconstitution hu-pbl-scid mice human il-3/gm-csf knock severe combined immunodeficiency human t-cell development hu-pbl-scid model nod/ltsz-scid mice hu-src-scid model ebv-related lymphoproliferative disorders nsg-hla tg mice nod-scid mice overcame nod-scid mice engraft provide human-specific t c57bl/6j-scid mice human-specific adhesion molecules b-17-scid/scid mice primary human t pmc beta search cd4 aptamer-sirna chimeras hiv-specific neutralizing iga human-specific infectious agents high-affinity ligand binding diphtheria toxin receptor hu-hsc nog mice xenogeneic graft-versus-host anti-cd122 monoclonal antibodies ii double-knockout mice limiting long-term studies b-cell cytokine blys identifying species-specific cytokines nod-scid miceβfail pmc copyright notice human species-specific cytokines generating nsg-ncf1null mice epstein barr virus enhance human hematopoietic nod/scid/gamma completely hla restricted b-cell responses hu-src-scid enhancing immune responses
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- Get to know https://scholar.google.com/scholar_lookup?journal=Exp%20Hematol&title=Regulation%20of%20human%20short-term%20repopulating%20cell%20(STRC)%20engraftment%20in%20NOD/SCID%20mice%20by%20host%20CD122+%20cells&author=LD%20Shultz&author=SJ%20Banuelos&author=J%20Leif&volume=31&publication_year=2003&pages=551-8&pmid=12829032&doi=10.1016/s0301-472x(03)00076-6&'s earnings
- What's the monthly money flow for https://scholar.google.com/scholar_lookup?title=NOD%20mice%20and%20related%20strains:%20research%20applications%20in%20diabetes,%20AIDS,%20cancer%20and%20other%20diseases&author=DL%20Greiner&author=LD%20Shultz&publication_year=1998&?
- How much does https://doi.org/10.1002/stem.160166 pull in monthly?
- Income figures for https://scholar.google.com/scholar_lookup?journal=Stem%20Cells&title=SCID%20mouse%20models%20of%20human%20stem%20cell%20engraftment&author=DL%20Greiner&author=RA%20Hesselton&author=LD%20Shultz&volume=16&publication_year=1998&pages=166-77&pmid=9617892&doi=10.1002/stem.160166&
- Financial intake of https://doi.org/10.1006/cimm.1996.0193
- Get to know what's the income of https://scholar.google.com/scholar_lookup?journal=Cell%20Immunol&title=Role%20of%20natural%20killer%20cells%20on%20engraftment%20of%20human%20lymphoid%20cells%20and%20on%20metastasis%20of%20human%20T-lymphoblastoid%20leukemia%20cells%20in%20C57BL/6J-scid%20mice%20and%20in%20C57BL/6J-scid%20bg%20mice&author=SW%20Christianson&author=DL%20Greiner&author=IB%20Schweitzer&volume=171&publication_year=1996&pages=186-99&pmid=8806787&doi=10.1006/cimm.1996.0193&
- What's the total monthly financial gain of https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=Multiple%20defects%20in%20innate%20and%20adaptive%20immunologic%20function%20in%20NOD/LtSz-scid%20mice&author=LD%20Shultz&author=PA%20Schweitzer&author=SW%20Christianson&volume=154&publication_year=1995&pages=180-91&pmid=7995938&?
- Profit of https://scholar.google.com/scholar_lookup?journal=Blood&title=Phenotype%20and%20function%20of%20human%20hematopoietic%20cells%20engrafting%20immune-deficient%20CB17-severe%20combined%20immunodeficiency%20mice%20and%20nonobese%20diabetic-severe%20combined%20immunodeficiency%20mice%20after%20transplantation%20of%20human%20cord%20blood%20mononuclear%20cells&author=F%20Pflumio&author=B%20Izac&author=A%20Katz&author=LD%20Shultz&author=W%20Vainchenker&volume=88&publication_year=1996&pages=3731-40&pmid=8916937&
- How much does https://scholar.google.com/scholar_lookup?journal=Am%20J%20Path&title=Improved%20engraftment%20of%20human%20spleen%20cells%20in%20NOD/LtSz-scid/scid%20mice%20as%20compared%20with%20C.B-17-scid/scid%20mice&author=DL%20Greiner&author=LD%20Shultz&author=J%20Yates&volume=146&publication_year=1995&pages=888-902&pmid=7717456& rake in every month?
- What's the revenue for https://doi.org/10.1093/infdis/172.4.974?
- Financial intake of https://scholar.google.com/scholar_lookup?journal=J%20Infect%20Dis&title=High%20levels%20of%20human%20peripheral%20blood%20mononuclear%20cell%20engraftment%20and%20enhanced%20susceptibility%20to%20human%20immunodeficiency%20virus%20type%201%20infection%20in%20NOD/LtSz-scid/scid%20mice&author=RM%20Hesselton&author=DL%20Greiner&author=JP%20Mordes&author=TV%20Rajan&author=JL%20Sullivan&volume=172&publication_year=1995&pages=974-82&pmid=7561218&doi=10.1093/infdis/172.4.974&
- Profit of https://doi.org/10.1111/j.1365-2249.2009.03933.x
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- How much profit does https://doi.org/10.4049/jimmunol.165.1.518 generate?
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- Profit of https://doi.org/10.1182/blood-2004-02-0656
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- What are the total earnings of https://scholar.google.com/scholar_lookup?51%E2%80%9378.%20See%20the%20Supplementary%20data%20online.?
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- Monthly income for https://www.nlm.nih.gov/web_policies.html
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