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Title[redir]:
Epigenetics and Psychiatry - PMC
Description:
Psychiatric disorders including major depressive disorder, drug addiction, and schizophrenia are debilitating illnesses with a multitude of complex symptoms underlying each of these disorders. In recent years, it has become appreciated that the ...
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Keywords {🔍}
doi, pubmed, google, scholar, epigenetic, expression, histone, schizophrenia, pmc, bdnf, article, methylation, gene, free, chronic, promoter, acetylation, dna, antidepressant, role, studies, mechanisms, reelin, cocaine, addiction, treatment, patients, depression, hdac, modifications, stress, brain, neurosci, disorders, behaviors, work, hippocampus, nac, psychiatric, genes, effect, psychiatry, drug, recent, regulation, behavior, exposure, mice, rac, development,
Topics {✒️}
linked brain-derived-neurotrophic factor brain-derived neurotrophic factor pmc beta search methylation-induced repression--belts early genes c-fos mediating long-term aspects mediating long-lasting adaptations electronic supplementary material 12-month dsm-iv disorders ventral tegmental area type-2 metabotropic glutamate brain circuitry induced cocaine-induced addiction behaviors glutamic acid decarboxylase67 aza-2′-deoxycytidine time-dependent increases histone deacetylase inhibition stress-related mood disorders trends pharmacol sci brain reward areas including histone acetyltransferases flinders sensitive line γ-aminobutyric acid license information pmcid cocaine increases expression supplementary materials included hdac inhibition activity long-term behavioral impact circuit level class ii hdac recent paper showed decreased mrna levels produce long-lasting united states government small rho-gtpase dorsal root ganglion conditioned place preference received notable attention pan-hdac inhibitor pyridin-3-yl-methoxycarbonyl landscape takes shape o'donovan mc di-giorgi-gerevini behavioral neuropathologies related peripheral blood lymphocytes chronic l-methionine administration social defeat stress rac1 expression selectively leave lasting marks influence gene activity
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