
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Fenofibrate lowers blood pressure in salt-sensitive but not salt-resistant hypertension - PMC
Description:
Peroxisome proliferator-activated receptor ฮฑ agonists reduce blood pressure in rodents, but clinical trials provide conflicting data regarding their effects in humans. We tested the hypothesis that the effect of fenofibrate on blood pressure depends ...
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Keywords {๐}
salt, fenofibrate, volunteers, saltsensitive, high, saltresistant, intake, doi, pressure, blood, low, placebo, urine, plasma, study, google, scholar, effect, compared, pubmed, significantly, hypertension, versus, eet, treatment, heart, rate, renal, pmc, eets, concentrations, mmhg, pra, patients, article, acid, decreased, excretion, pparฮฑ, reduced, diabetes, antihypertensive, map, table, effects, sensitivity, activity, dbp, higher, free,
Topics {โ๏ธ}
peroxisome proliferator-activated receptor selective ppar-alpha agonist para-aminohippuric acid renal vascular resistance renal plasma flow high-performance liquid chromatography reducing vascular resistance plasma renin activity nonsteroidal anti-inflammatory drugs young sprague-dawley rats angiotensin receptor blocker sodium-modulated tissue responsiveness angiotensin ii-infused rats renal thiazide/amiloride sensitivity concurrent angiotensin-converting enzyme long-term fenofibrate therapy pmc beta search t-test approach proposed dahl salt-sensitive rats plasminogen activator inhibitor soluble epoxide hydrolase urine dhets/dhets+eets tended urine epoxyeicosatrienoic acid dihydroxyeicosatrienoic acid conflicts salt-sensitive volunteers resulted salt-sensitive volunteers suggests renal cyp2c expression dahl salt-sensitive rat high-density lipoprotein pmc copyright notice reducing vasoconstriction mediated overt renal insufficiency plasma dihydroxyphenylacetic acid salt-sensitive volunteers compared reninโangiotensin salt-resistant volunteers compared angiotensin-converting enzyme salt-sensitive hypertensive individuals salt-sensitive hypertensive patients fenofibrate increased activity convey increased risk publisher site pdf provide information robust salt-sensitive volunteers weighed salt-sensitive essential hypertension salt-resistant hypertensive patients 20-hydroxyeicosatetraenoic acid ]-20-hydroxyeicosatetraenoic acid pparalpha null mice
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