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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC378509/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC378509/. The analysis below is for the second page.

Title[redir]:
Deactivation of peroxisome proliferator–activated receptor-α during cardiac hypertrophic growth - PMC
Description:
We sought to delineate the molecular regulatory events involved in the energy substrate preference switch from fatty acids to glucose during cardiac hypertrophic growth. α1-adrenergic agonist–induced hypertrophy of cardiac myocytes in culture ...

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Education
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Custom-built

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🌠 Phenomenal Traffic: 5M - 10M visitors per month

Based on our best estimate, this website will receive around 6,398,900 visitors per month in the current month.

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While many websites aim to make money, others are created to share knowledge or showcase creativity. People build websites for various reasons. This could be one of them. Ncbi.nlm.nih.gov has a secret sauce for making money, but we can't detect it yet.

Keywords {🔍}

pparα, cardiac, doi, gene, expression, myocytes, myocyte, pubmed, google, scholar, activity, fatty, hypertrophy, figure, fao, lipid, results, control, mcpt, shown, pmc, hypertrophic, pathway, reduced, oleate, experiments, growth, response, hypertrophied, usa, acid, mice, cells, article, oxidation, mitochondrial, receptor, free, peroxisome, studies, performed, cell, rat, regulatory, energy, myocardial, vehicle, transfection, kinase, heart,

Topics {✒️}

long-chain acyl-coa dehydrogenase peroxisome proliferator–activated receptor-α α1-adrenergic agonist–induced hypertrophy mitogen-activated protein kinase α1-adrenergic agonist–mediated repression ligand-independent trans-activating domain nh2-terminal ab domain peroxisome proliferator-activated receptor rat acyl-coa oxidase fatty acid–activated m-cpt fatty acid–induced m-cpt peroxisome proliferator-responsive elements long-chain fatty acids cotransfected psv40–β-gal plasmid medium-chain acyl coenzyme fatty acid-metabolizing enzymes lipid-activated nuclear receptor fatty acid–induced transcription protein–coupled receptor activation α1-adrenergic agonist pe cardiac-specific gene expression map kinase-mediated phosphorylation gelatin-coated cover slips galacto-light chemiluminescence assay pressure overload–induced hypertrophy fatty acid–stimulated expression α1-adrenergic agonist receptor-dna binding motifs anti-flag m2 antibody homologous promoter–reporter plasmid mapk pathway–selective inhibitors signal transduction circuits pmc beta search oleate/pparα-responsive element fare-1 standard luciferin-atp assay cotransfected psv40–β-gal β-galactosidase gene downstream steady-state m-cpt protein kinase cascades pmc copyright notice erk-mapk pathway blocks psv40–β-gal activity including erk-mediated phosphorylation dominant-negative ras experiments fatty acid oxidation pe-induced myocyte hypertrophy rat hydratase/dehydrogenase pressure-overloaded left ventricle muscle carnitine palmitoyltransferase calcineurin-dependent transcriptional pathway

Questions {❓}

Life after calcineurin?

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