
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Fusobacterium nucleatum potentiates intestinal tumorigenesis and modulates the tumor immune microenvironment - PMC
Description:
Increasing evidence links the gut microbiota with colorectal cancer. Metagenomic analyses indicate that commensal Fusobacterium spp. are associated with human colorectal carcinoma but whether this is an indirect or causal link remains unclear. We ...
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Keywords {🔍}
doi, fusobacterium, nucleatum, colorectal, mice, cells, cancer, tumor, cell, tumors, pubmed, google, scholar, human, pmc, intestinal, article, figure, apcmin, free, abundance, tumorigenesis, immune, colonic, adenomas, data, gene, fed, spp, myeloid, tissue, expression, mouse, enriched, analysis, relative, small, increased, progression, colon, samples, compared, colitis, bacterial, shown, crc, kostic, patients, fusobacteria, normal,
Topics {✒️}
/nf-kb/gene-resources/target-genes/ including formyl-methionyl-leucyl-phenylalanine 1µg/ml anti-cd28 antibody nf-κb-driven pro-inflammatory response 1µg/ml anti-cd3 antibody mg+-free dpbs myeloid-derived suppressor cells eliciting pro-tumorigenic responses retinoic acid-dependent mechanism pmc beta search steroidal anti-inflammatory drugs tumor-infiltrating immune cells dna-free™ kit pro-inflammatory expression signature fluorochrome-conjugated monoclonal antibodies gov/docs/publications/coadread_2012/ nf-κb proinflammatory signature cell number/gram tumor bacterial driver–passenger model cd11b+gr-1macrophage population tumor-permissive myeloid cells p65 nf-κb subunit inflammation-related gene functions promote anti-tumor immunity increased nf-κb activation dampen anti-tumor immunity cell host microbe pro-inflammatory genes identified supplementary materials included examine nf-κb activation vander heiden azoxymethane-injected il10−/− mice adjacent normal tissue mucosal adherent bacteria references arthur jc pro-inflammatory signature microbial gene function cancer genome atlas 1 mg/ml collagenase universal eubacteria 16s adenoma-linked barrier defects myeloid immune cells enterotoxigenic bacteroides fragilis parametric mann-whitney cancer prevention research specific bacterial strain host gene expression cell suppressive activity immune cell function blood vessel growth
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- Colorectal cancer: CRC-all about microbial products and barrier function?
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Analytics and Tracking {📊}
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