
NCBI . NLM . NIH . GOV {
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Title[redir]:
The Major Brain Endocannabinoid 2-AG Controls Neuropathic Pain and Mechanical Hyperalgesia in Patients with Neuromyelitis Optica - PMC
Description:
Recurrent myelitis is one of the predominant characteristics in patients with neuromyelitis optica (NMO). While paresis, visual loss, sensory deficits, and bladder dysfunction are well known symptoms in NMO patients, pain has been recognized only ...
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Keywords {🔍}
pain, patients, nmo, google, scholar, pubmed, doi, neuropathic, mechanical, sensory, spinal, central, thresholds, healthy, heat, thermal, hyperalgesia, threshold, cord, qst, detection, pmc, feet, controls, lesions, article, testing, data, cold, free, sensitivity, log, significantly, brain, neuromyelitis, somatosensory, optica, signs, lesion, fig, injury, loss, dfns, plasma, depression, abnormal, levels, significant, cannabinoid, hands,
Topics {✒️}
yates corrected chi-square web-based statistical freeware funding statement yates-corrected chi2-test pmc beta search glia-induced reversible disruption cannabinoid lipids n-arachidonoylethanolamide blood-brain barrier integrity epidemiological studies-depression scale gender-matched healthy controls cross-sectional study exploring synaptic long-term depression mri-verified signs alternating warm/cold stimulation posttraumatic stress disorder full-blown hyperalgesia multicenter cross-sectional study deafferentation-induced neuropathic pain small single lesion patients/subjects exhibiting dma endocannabinoid-dependent plasticity patients/subjects exhibiting phs spinal dorsal horn major endogenous cannabinoid nonspecific white matter peripheral nerve injury license information pmcid spinal cord injury eleven consecutive patients scale reflecting impairment dynamic mechanical allodynia spinal cord lesion cannabinoid drugs acting spinal cord inflammation lipid signalling molecules cb1 cannabinoid receptors cervical spinal lesion endocannabinoid 2-arachidonoyl glycerol endogenous cannabinoid 2-arachidonoylglycerole validated questionnaire evaluating net/sisa/binomial publisher site pdf gender-matched group retrograde negative feedback measure reflecting pain patients showed lesions aquaporin-4 water channel painful dysesthesias elicited achieve timely recognition nonopioid placebo analgesia
Questions {❓}
- (2008) Neuropathic pain: are there distinct subtypes depending on the aetiology or anatomical lesion?
- Susser E, Sprecher E, Yarnitsky D (1999) Paradoxical heat sensation in healthy subjects: peripherally conducted by A{delta} or C fibres?
- Voscopoulos C, Lema M (2010) When does acute pain become chronic?
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