
NCBI . NLM . NIH . GOV {
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Title[redir]:
Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse - PMC
Description:
Bone marrow-derived endothelial progenitor cells (EPCs) are critical for metastatic progression. This study explores the effect of tetrathiomolybdate (TM), an anti-angiogenic copper chelator, on EPCs in patients at high risk for breast cancer ...
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Keywords {π}
patients, doi, cancer, copper, breast, stage, google, scholar, pubmed, triplenegative, tumor, epcs, cells, pmc, depletion, relapse, study, baseline, article, therapy, copperdepleted, angiogenesis, free, ned, endothelial, progenitor, tetrathiomolybdate, grade, levels, disease, range, metastatic, angiogenic, months, figure, bone, progression, patient, toxicity, trial, res, mgdl, target, luminal, significant, growth, decreased, treatment, time, significantly,
Topics {βοΈ}
her2/neu-induced breast carcinoma gr-1+cd11b+ myeloid cells triple-negative patients copper-depleted temporarily rendered disease-free sigma-aldrich chemical company ficoll density-gradient centrifugation enzyme-linked immunosorbent assay patients remain relapse-free anti-angiogenic copper chelator triple-negative breast cancer pmc beta search marrow-derived endothelial positive versus triple-negative node-positive breast cancer her2-negative breast cancer triple-negative patients compared 10-month relapse-free survival copper-depleted patients spent epc-mediated angiogenic switch endothelial progenitor cells hypoxia-induced lysyl oxidase vascular adhesion protein-1 bone marrow niche triple-negative subset [lack drug-related adverse events primary breast cancer meso scale discovery hemangiogenic progenitor cells adequately copper-deplete relapse-free survival breast cancer cells human breast cancer advanced kidney cancer supplementary materials included publisher site pdf cancer online resources complete metabolic panel endothelial cell projections endothelial cell turnover [google scholar] 2 triple-negative patients triple-negative patients [34 11 triple-negative patients tumor cell proliferation stage 3 triple-negative hematopoietic stem cells translational studies demonstrating recurrent breast cancer breast cancer metastases invasive breast cancer
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