
NCBI . NLM . NIH . GOV {
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Title[redir]:
Normal cognition in transgenic BRI2-Aβ mice - PMC
Description:
Recent research in Alzheimer’s disease (AD) field has been focused on the potential role of the amyloid-β protein that is derived from the transmembrane amyloid precursor protein (APP) in directly mediating cognitive impairment in AD. Transgenic ...
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Keywords {🔍}
mice, doi, briaβ, memory, google, scholar, pubmed, app, test, mouse, amyloid, transgenic, cognitive, figure, pmc, fear, models, brain, spatial, article, results, months, nontg, levels, age, free, tests, showed, conditioned, significant, study, table, pathology, taste, genotype, water, learning, sex, saccharine, alzheimers, disease, model, deficits, deposition, training, tested, search, behavior, tone, crnd,
Topics {✒️}
hybrid c57/b6//c3h background sds-page resolved samples n-methyl-d-aspartate receptor competing financial interests references eriksen jl generate bri2-aβ1-40/aβ1-42 mice aav-bri2-aβ injected rats bri2-aβ1-40/ bri2-aβ1-42 mice amyloid precursor protein-transgenic competing interests β-carboxyl-terminal fragments amino-terminal-soluble appβ aav-mediated gene transfer pmc beta search virally-mediated gene transfer greenhouse-geisser epsilon correction enzyme-linked immunosorbent assay full-length human app β-secretase cleaved fragments bri2-aβ1-42 mice showed exogenous amyloid-beta peptides aav-bri2-aβ1-42 rats collect sds-soluble fractions cohesive gender-based etiology abbreviations aβ license information pmcid long-term fear memory bri2-aβ transgenic mice bri2-aβ1-42 mice show bri2-aβ1-42 mice tended affect long-term potentiation beta-amyloid infusion results bri2-aβ mouse models anti-β-actin antibody respective bri2-aβ transgenes collect ripa-soluble fractions bri2 fusion strategy bri2-aβ1-42 group died develop amyloid deposits bri2-aβ1-42 mice forebrain bri2-aβ1-40/aβ1-42 mice anti-total aβ antibody amyloid precursor proteins studies bri2-aβ line alzheimer beta-amyloid pathology amyloid precursor protein bri2-aβ1-42 mice observed 5% tris-tricine gel publisher site pdf bri2-aβ lines tested
Questions {❓}
- Hippocampal synaptic plasticity: role in spatial learning or the automatic recording of attended experience?
- The culprit behind amyloid beta peptide related neurotoxicity in Alzheimer's disease: oligomer size or conformation?
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