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Keywords {🔍}

doi, succination, aco, fumarate, protein, fhko, mefs, cell, google, scholar, aconitase, pubmed, mitochondrial, activity, cells, figure, cysteine, residues, proteins, pmc, article, succinated, fragment, ion, mass, free, targets, cycle, performed, fhdeficient, data, tissue, adam, cancer, metabolism, analyses, fhwt, citrate, krebs, dehydrogenase, isoform, oflaherty, cellular, previously, frizzell, soga, cluster, mitochondria, peptide, analysis,

Topics {✒️}

isoforms β\δ\ε\γ fh1 fl/fl ksp-cre iron-sulfur-binding cysteine residues iron-sulfur cluster assembly dose-dependent fumarate-mediated succination iron-sulfur cluster binding supplemental information mmc1 performed lc-ms/ms analyses thioredoxin-dependent peroxide reductases cdgsh iron-sulfur domain oncogenic hif-dependent pathways c-terminal fragment ion n-terminal fragment ion thioredoxin-dependent peroxide reductase pef1/v5-hisa vector creatine kinase u-type pmc beta search δ-1-pyrroline-5-carboxylate synthase lc-ms/ms analyses open-access article distributed bifunctional aminoacyl-trna synthetase fumarate-mediated succination occurs monofunctional c1-tetrahydrofolate synthase 2og-dependent oxygenases similar [google scholar] schneider egg jelly-related protein rna-binding protein raly repeated ms/ms analysis iron-binding cysteine residues lc-ms/ms analysis s-methyl-5′-thioadenosine phosphorylase histone-binding protein rbbp7 extended experimental procedures deuterium-labeled [d5]glutamine probability-based protein identification scaffold attachment factor license information pmcid free sulfhydryl groups diverse cellular pathways iron response element fh-deficient cells leads fumarate hydratase-deficient cells glutamine-dependent reductive mechanism references adam fumarate hydratase-deficient mice full ms scan v5-tagged aco2 gene label-free quantitation atomic force microscopy trypsin-digested aco2 derived

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