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Keywords {🔍}

abt, doi, bim, bcl, mice, pubmed, google, scholar, days, treatment, tumor, pmc, mcl, day, figure, article, cell, blood, lymphomas, proteins, inhibitor, treated, tumors, mimetic, bhonly, cancer, survival, supplemental, bortezomib, apoptosis, cells, data, free, nlm, transplanted, vivo, thrombocytopenia, purvalanol, bclxl, mycbcl, lymphoma, vehicle, ncbi, search, therapy, navitoclax, cdk, noxa, levels, combination,

Topics {✒️}

aggressive myc-driven lymphomas targeted high-affinity inhibitor pmc beta search c-myc oncogene driven kaplan-meier survival curves eμ-myc/eμ-bcl-2 bcl-2–specific bh3 mimetic bcl-2–dependent tumor types programmed cell death cyclin-dependent kinase chronic lymphocytic leukemia bitransgenic myc/bcl-2 mice long-term exposure eliza hall institute proteasome inhibitor-induced apoptosis antiapoptotic bcl-2–related proteins page charge payment immunocompetent tumor-bearing mice nonirradiated c57bl/6 recipients supplementary materials included bcl-2–selective inhibitor selective bcl-2 inhibitor bcl-xl provokes thrombocytopenia cell death differ united states government procedures involving animals license information pmcid infrastructure support myc/bcl-2 lymphomas acute myeloid leukemia eμ-myc tumors tripartite research collaboration stress apoptosis pathway efficiently induces apoptosis enforced bcl2 expression myc-overexpressing cells bcl-2 family proteins drugs acted rapidly close relatives bax outer mitochondrial membrane standardized phosphatidylcholine concentrate induces higher expression comparatively short relative previously published data12 excellent technical assistance medical research council competing financial interests 1g royal parade van delft mf del gaizo moore

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