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Title[redir]:
Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet? - PMC
Description:
There have been substantial advances in cancer diagnostics and therapies in the past decade. Besides chemotherapeutic agents and radiation therapy, approaches now include targeting cancer cell–intrinsic mediators linked to genetic aberrations in ...
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Keywords {🔍}
doi, cells, google, scholar, pubmed, cancer, pmc, tumor, cell, article, free, immune, inflammation, tissue, macrophages, therapeutic, chronic, cytotoxic, fig, tumors, responses, breast, dcs, med, immunol, clin, nature, activated, development, myeloid, factor, jccr, nlm, science, coussens, clinical, factors, type, growth, death, survival, tumorpromoting, agents, leading, leukocytes, leukocyte, tnfα, expression, chemotherapy, disease,
Topics {✒️}
inflammasome-related il-1β/il-18 correlate blunting nf-κb/stat3/phosphatidylinositol 3-kinase granulocyte-macrophage colony-stimulating factor transforming growth factor–β cxcr4/cxcl12 chemokine axis age-related cellular senescence csf-1–related gene signatures pmc beta search neutralizing tumor-promoting inflammation secrete matrix-remodeling proteins cell–derived paracrine factors reinvigorates virus-specific cd8+ immune complex/fcγ receptors reed-sternberg cells growth stat3/nf-κb pathway tumor-specific inflammatory mechanisms tumor regrowth post-therapy induce immune-mediated rejection late-stage mammary adenocarcinomas il-13 receptor–dependent signaling canonical wnt program ecm-sequestered mitogenic agents publisher site pdf anti-apoptotic pathways cancer-promoting chronic inflammation myeloid-based immunosuppressive molecules cancer-induced chronic inflammation activates tissue-resident macrophages regulating vascular programming tumor-infiltrating myeloid cells cancer inflammation–induced cytokines cell–dependent skin carcinogenesis cancer cell–extrinsic pathways major protumor effects promotes th1 responses hypoxia-inducible factor 1 cell effector responses [google scholar] 21 [google scholar] 34 [google scholar] 45 [google scholar] 72 cancer-derived factors macrophages fosters pro-angiogenic epidermal growth factor blunting cell death pathogenic tslp/il-13 pathway immune checkpoint molecules fibroblast growth factors tumor necrosis factor tumor-promoting capabilities
Questions {❓}
- A magic bullet?
- Neutralizing Tumor-Promoting Chronic Inflammation: A Magic Bullet?
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- See how much https://doi.org/10.1016/j.coi.2007.01.001 makes per month
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- https://doi.org/10.1158/1078-0432.CCR-12-1149's financial summary
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