
NCBI . NLM . NIH . GOV {
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Title[redir]:
Bmi-1 Promotes Glioma Angiogenesis by Activating NF-κB Signaling - PMC
Description:
Angiogenesis in glioma is associated with the poor prognosis of the disease and closely correlates with the highly invasive phenotype of glioma cells, which represents the most challenging impediment against the currently glioma treatments. Bmi-1, ...
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Keywords {🔍}
cells, bmi, glioma, expression, angiogenesis, vegfc, doi, pubmed, google, scholar, nfκb, figure, gliomas, tumor, cancer, pmc, cell, huvec, data, signaling, article, control, assay, human, activity, vitro, bmioverexpressing, free, induced, quantification, promotes, brain, migration, performed, progression, role, formation, genes, usa, levels, images, left, mrna, vector, analysis, treated, vectorcontrol, vivo, independent, previously,
Topics {✒️}
pi-3k/akt/gsk-3β pathway [14] ikk-nuclear factor-kappab pathway real-time rt-pcr pmc beta search nf-κb-regulated gene expression psuper-retro-puro-vector lipopolysaccharide-induced nuclear translocation nf-κb binding site induces epithelial-mesenchymal transition nf-kappab motif drives real-time pcr analysis activating nf-κb signaling nf-κb signaling pathway cancer-related signaling pathways real-time pcr quantification enzyme-linked immunosorbent assay acute myeloid leukemia releasing matrix-bound vegf identify diagnostic/prognostic biomarkers prl-tk renilla plasmid nf-κb transcriptional activity matrix metalloproteinase-9 triggers functional nf-κb activation nf-κb target genes bmi-1-induced glioma angiogenesis supplementary materials included bmi-1-specific rna interference bmi-1-silenced glioma cells bmi-1-overexpressing glioma cells methods ethics statement primary brain tumors mu-myc transgenic mice promotes cell proliferation brain glioma-bearing mice bmi-1-silencing glioma cells nf-κb pathway nf-κb signaling induce tubule formation pro-angiogenic activities stimulated huvec migration ink4a-arf locus expression including cell proliferation publisher site pdf license information pmcid nf-κb activity bmi-1 suppresses transcription nf-κb inhibitor huvec tubule formation shrna-mediated knockdown huvec cell migration
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