
NCBI . NLM . NIH . GOV {
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Title[redir]:
Anticancer activity of cardiac glycosides: At the frontier between cell-autonomous and immunological effects - PMC
Description:
Retrospective clinical data indicate that cardiac glycosides (CGs), notably digoxin, prolong the survival of carcinoma patients treated with conventional chemotherapy. CGs are known to influence the immune response at multiple levels. In addition, ...
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Keywords {π}
digoxin, doi, cgs, cancer, patients, cells, cell, cardiac, pubmed, google, scholar, pmc, effects, atpase, human, clinical, nak, glycosides, nlm, activity, carcinoma, death, icd, ncbi, search, anticancer, immunogenic, endoplasmic, reticulum, study, survival, intracellular, release, inhibit, secretion, users, rorΞ³t, free, article, retrospective, chemotherapy, immune, response, results, effect, calreticulin, digitoxin, hmgb, subunits, tumor,
Topics {βοΈ}
cisplatin-based chemo/radiotherapy regimens th17-dependent autoimmune diseases interferon-Ξ² gene expression pmc beta search mediate anti-inflammatory effects cg-induced icd originates publisher site pdf tumor-specific immune response immunogenic cell death interferon Ξ² secretion nuclear protein hmgb1 gene encoding interleukin-17 nat chem biol hormone receptor status retinoic acid receptor united states government license information pmcid 5-trisphosphate-gated channels de facto improving rna sensor rig double-stranded rna double-stranded dna institut gustave roussy developing uterus cancer crit pathw cardiol sci transl med clinical data suggest transfect human cells large study enrolling patients receiving drugs develop prostate cancer fda-approved drugs congestive heart failure de facto improves subgroup analyses revealed acute myeloid leukemia specifically inhibit rorΞ³t prostate cancer patients cg-mediated cytotoxicity cg-resistant variant pre-apoptotic exposure dna-damaging agents cancer therapeutic agents underlying cardiac disorder underlying cardiac pathology prospective clinical trial mediate antineoplastic effects developing breast cancer clinical anticancer activity colorectal carcinoma patients
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