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Title[redir]:
Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism - PMC
Description:
Carnitine Palmitoyltransferase-1c (CPT1c) is a neuron specific homologue of the carnitine acyltransferase family of enzymes. CPT1 isoenzymes transfer long chain acyl groups to carnitine. This constitutes a rate setting step for mitochondrial fatty ...
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Keywords {🔍}
cptc, metabolism, mice, carnitine, doi, fatty, acid, role, oxidative, pubmed, metabolomic, google, scholar, free, pmc, food, metabolites, figure, intake, stress, results, brain, pathway, showed, article, brains, biochemicals, chain, mitochondrial, endocannabinoids, levels, decrease, neurons, involved, oxidation, significant, enzymes, cpt, long, acyl, mouse, palmitoyltransferase, metabolic, energy, cells, profiling, betaoxidation, analysis, function, phosphate,
Topics {✒️}
brain-specific carnitine palmitoyl-transferase-1c long chain acyl-coa carnitine palmitoyltransferase-1c gain pmc beta search medium-chain acyl-coa anti-rabbit horseradish peroxidase competing interests short-term food deprivation fatty acid beta-oxidation brain-specific carnitine palmitoyltransferase gas chromatography/mass spectrometry exhibited diet-induced obesity mouse monoclonal anti-hsc70 malonyl-coa insensitive cpt2 abbreviations wt general platform methods fatty acid catabolism regulates food intake gamma-glutamyl redox cycle oxidative stress-induced apoptosis discussion role publisher site pdf license information pmcid identified stress-induced manner decreased free carnitine free carnitine decreased 1549099 n-acetyl-aspartyl-glutamate brain-expressed protein related acyl chain back redox homeostasis including fatty acid oxidation wolfgang mj elevated oxidative demands high fat diet high-fat diet [10] tissue-specific manner essential fatty acid facilitate acyl transfer affect retaining information bcr-abl survival fatty acid biochemistry neuron specific homologue neuronal oxidative metabolism fatty acid metabolism long chain follow acknowledgments low-fat diet [6 regulate food intake leptin hypothalamic control
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