NCBI . NLM . NIH . GOV {
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We began analyzing https://pmc.ncbi.nlm.nih.gov/articles/PMC3446710/, but it redirected us to https://pmc.ncbi.nlm.nih.gov/articles/PMC3446710/. The analysis below is for the second page.
Title[redir]:
Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7) - PMC
Description:
Precursor let-7 miRNAs are degraded in undifferentiated cells and cancer cells in the presence of the small RNA-binding protein Lin28 and the Terminal Uridyl Transferase (TUTase) Zcchc11/TUTase 4. While recent efforts have focused on the role of ...
Title[redir]:
Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7) - PMC
Description:
Precursor let-7 miRNAs are degraded in undifferentiated cells and cancer cells in the presence of the small RNA-binding protein Lin28 and the Terminal Uridyl Transferase (TUTase) Zcchc11/TUTase 4. While recent efforts have focused on the role of ...
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Keywords {🔍}
zcchc, lin, uridylation, doi, scholar, pubmed, google, prelet, activity, pmc, cell, rna, cells, article, vitro, free, stem, expression, zinc, tutase, domains, proteins, microrna, mirna, domain, pree, required, mirnas, protein, fig, levels, embryonic, finger, tutases, linenhanced, mature, site, piskounova, assays, recombinant, control, cancer, heo, similar, sufficient, micrornas, rnas, hagan, synthetic, letg,
Topics {✒️}
taqman-based real-time pcr single-stranded heptad sequence 125 nm [α-32p]utp pmc beta search cis-acting elements double-negative feedback loop glutamine-rich neurodegenerative disease mouse anti-flag antibody rna-specific ribonucleotidyl transferases rna-interference enzyme dicer full-length zcchc11 cdna target rna-directed trimming neural stem-cell commitment anti-flag m2 beads n-terminal c2h2 domain end-labeled synthetic pre important rna-modifying enzyme org/cgi/doi/10 supports lin28-enhanced uridylation additional c-terminal truncations important post-transcriptional regulators feeder-free v6 cold-shock domain n-terminal trf4 domain n-terminal trf4/pap mirna-induced silencing complex uridylating mature mir-26a sequence-specific rna binding pew research scholar mediate lin28-enhanced activity flag-hzcchc11 wild type blocks pri-mirna processing cchc zinc finger cchc zinc fingers cytoplasmic lin28-interacting tutase intact pre-mirna stem flag-ip wt mzcchc11 wt flag ip-mzcchc11 mediates lin28-dependent uridylation c2h2 zinc finger lin28-expressing cells leads sequence-specific recognition factors lin28-enhanced uridylation activity van wolfswinkel mediate lin28-dependent pre intact pre-mirna structure western blot analysis full-length pre drosha-dgcr8 complex rnase iii enzyme
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