
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Early G1 cyclin-dependent kinases as prognostic markers and potential therapeutic targets in esophageal adenocarcinoma - PMC
Description:
Chromosomal gain at 7q21 is a frequent event in esophageal adenocarcinoma (EAC). However, this event has not been mapped with fine resolution in a large EAC cohort and its association with clinical endpoints and functional relevance are unclear. We ...
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Keywords {π}
cdk, doi, expression, cell, eac, amplification, survival, cancer, pubmed, google, scholar, figure, cells, tumors, lines, genes, gene, prb, proliferation, analysis, data, amplicon, pmc, cycle, tumor, sirna, res, adenocarcinoma, association, patients, growth, cyclindependent, kinase, targeting, probesets, article, shown, effect, esophageal, poor, amplified, breast, inhibition, activity, disease, high, human, patient, total, prognostic,
Topics {βοΈ}
mitogen-dependent early g1-phase hsa-mir-124a locus mammalian cyclin-dependent kinases d-type cyclins-cdk4/6-prb breast cancer genomes--form frequent high-level amplifications kaplan-meier survival estimates western blot showing hgf/met signalling pathway cyclin-dependent kinase inhibitors pmc beta search hsa-mir-124a copy number gain fluorescence-activated cell sorting mammalian cell-cycle regulation rb/e2f1 complex leading anchorage independent growth anchorage-independent growth kaplan meier plots cdk6/cyclin d1 complex early g1 phase cyclin-dependent kinase 6 cyclin-dependent kinases cyclin-dependent kinase 4/6 cyclin-dependent kinases 4 tumor suppressor protein human tumor xenografts high copy gains nih grant r01ca130853 cell cycle analysis d-type cyclins clin cancer res log relative hazard cell cycle progression cyclin d1-cdk4/6 activity cell cycle regulator cell cycle regulators license information pmcid proportional hazards regression show similar improvement single institution experience publisher site pdf dose-dependent manner dna-reactive drugs cdk inhibitor seliciclib recurrence-free survival current chemotherapy regimens site-specific phosphorylation suppressing cell proliferation acute lymphoblastic leukemia
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Analytics and Tracking {π}
- Google Analytics
- Google Analytics 4
- Google Tag Manager
Libraries {π}
- jQuery
- jQuery module (jquery-3.6.0)
- Zoom.js
Emails and Hosting {βοΈ}
Mail Servers:
- nihcesxway.hub.nih.gov
- nihcesxway2.hub.nih.gov
- nihcesxway3.hub.nih.gov
- nihcesxway4.hub.nih.gov
- nihcesxway5.hub.nih.gov
Name Servers:
- dns1-ncbi.ncbi.nlm.nih.gov
- dns2-ncbi.ncbi.nlm.nih.gov
- lhcns1.nlm.nih.gov
- lhcns2.nlm.nih.gov
CDN Services {π¦}
- Ncbi