
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Differential Transcriptional Programming of Class-Specific B Cell Memory by T-bet and RORα - PMC
Description:
Antibody class defines function in B cell immunity, but how class is propagated into B cell memory remains poorly understood. Here, we demonstrate that memory B cell subsets unexpectedly diverge across antibody class through the differential impact ...
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Keywords {🔍}
cells, memory, cell, igga, doi, tbet, expression, fig, iga, mice, pubmed, google, scholar, pmc, rorα, igg, article, panel, bcr, total, free, mrna, npspecific, left, day, plasma, oht, immunol, antibody, tbx, expressed, classspecific, rag, vivo, survival, transcription, development, bcl, science, class, antigenspecific, response, control, transcriptional, grcdcd, germinal, treated, days, function, antigen,
Topics {✒️}
gr1−cd4−cd8− igm−igd−cd19+b220+cd138−cd38+ gr1−cd4−cd8− igm+igd+ cd19+b220+ gr1−cd4−cd8− igm−igd− cd19+cd138− phycoerythrin-cy5-conjugated anti-gr-1 horizon v500-conjugated anti-cd8 np-klh gated gr1−cd4−cd8− allophycocyanin-cy7-conjugated anti-cd19 phycoerythrin-cy7-conjugated anti-cd45 phycoerythrin-cy7-conjugated anti-cxcr3 fluorescein isothiocyanate-conjugated anti-igg1 phycoerythrin-conjugated anti-t-bet orphan receptor-mediated transcription retinoid-related orphan receptors cells induces t-bet-dependent long-term immune protection equivalent np-binding cd138−b220+ cell-intrinsic t-bet expression allophycocyanin-conjugated anti-np peridinin-chlorophyll protein-cy5 alum-precipitated protein vaccine biotin-conjugated anti igg2ab biotin-conjugated anti-igg2ab n-ethyl-n-nitrosourea ifn-γ–induced stat1 activation pacific blue-conjugated igd phycoerythrin-conjugated anti-cd138 pmc beta search ongoing class-specific requirements class-specific cd38+b220hi splenocytes long-lived antigen-experienced allophycocyanin-conjugated anti-cd138 antigen receptor-intrinsic costimulation gr1−cd4−cd8−cd138+ function requires t-bet transcriptional regulators t-bet tgf-beta receptor controls np+igg2a+ memory b220hicd38+cd138− ifn-γ induced production biotin-conjugated anti-igg2b biotin-conjugated anti-iga temporally delete t-bet t-bet target genes23 t-bet-defined subset fluorescein isothiocyanateconjugated anti-cd45 biotin-conjugated anti-igg1 biotin-labeled monoclonal antibodies initiate antibody class-switch35 primary np-specific response biotin-conjugated anti-cd45 antibody class-specific manner35
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Analytics and Tracking {📊}
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