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Title[redir]:
Enlightening the impact of immunogenic cell death in photodynamic cancer therapy - PMC
Description:
EMBO J 31 5, 1062β1079 (2012); published online January 17 2012 In this issue of The EMBO Journal, Garg et al (2012) delineate a signalling pathway that leads to calreticulin (CRT) exposure and ATP release by cancer cells that succumb to ...
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Keywords {π}
cell, cells, icd, death, pmc, doi, garg, exposure, hyppdt, crt, atp, pubmed, google, scholar, response, nlm, kroemer, immune, zitvogel, embo, immunogenic, cancer, release, molecular, secretion, ncbi, search, article, signalling, kepp, stress, inducers, pathways, free, journal, galluzzi, pathway, calreticulin, anthracyclines, preapoptotic, surface, required, human, dcs, demonstrated, pik, shown, tumor, photodynamic, therapy,
Topics {βοΈ}
cholesterol-depleting agent methyl-Ξ²-cyclodextrine pan-caspase blocker z-vad hyp-pdt-treated t24 cells hyp-pdt-induced crt exposure hyp-pdt-elicited atp secretion 1o2 quencher l-histidine heat-shock protein hsp90 important antigen-presenting cells pmc beta search add hypericin-based ptd hyp-pdt stimulates icd tumor-specific immune response reactive oxygen species hyp-pdt activated dcs pro-apoptotic molecules bax pre-apoptotic calreticulin exposure hyp-pdt induced publisher site pdf t24 cells treated human dendritic cells tumor cell death hyp-pdt depended t24 cells exposed cytosolic ca2+ chelators anthracycline-induced icd license information pmcid murine jawsii dcs immunogenic cell death including photodynamic therapy pre-apoptotic exposure signalling pathways elicited stimulus-dependent fashion anthracycline-based chemotherapy cell death subroutines chemical inhibitor wortmannin efficient anticancer immunity signalling pathways leading nuclear protein hmgb1 united states government providing fresh insights spatiotemporally defined combination post-apoptotic release featuring high levels secrete high levels producing antineoplastic cd8+ rnai-mediated depletion microtubular poison nocodazole el-deiry ws improved clinical outcome pre-apoptotic secretion
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