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Title[redir]:
Antiproliferative Effect of Aaptamine on Human Chronic Myeloid Leukemia K562 Cells - PMC
Description:
We previously isolated aaptamine, a benzonaphthyridine alkaloid, from marine sponge Aaptos suberitoids. In this study, we investigated the anti-proliferative effect of aaptamine on chronic myeloid leukemia (CML) K562 cells. Aaptamine inhibited ...
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Keywords {🔍}
cells, aaptamine, doi, cell, pubmed, google, scholar, effect, promoter, treatment, marine, cml, cycle, assay, activity, incubated, antiproliferative, human, chronic, expression, figure, sponge, phase, luciferase, pmc, nlm, kong, growth, cancer, kobayashi, previously, analysis, concentrations, control, kit, ncbi, search, leukemia, isolated, induced, wst, absorbance, blank, myeloid, alkaloid, aaptos, inhibited, transfected, pindependent, kinase,
Topics {✒️}
anti-mouse hrp-conjugated antibody anti-cip1/waf-1/p21 antibody anti-mouse horseradish peroxidase dna-prep reagents kit anti-cip1/waf-1/p21 inhibitor targeting bcr-abl k562 cells dose-dependently cyclin-dependent kinase inhibitors sds-polyacrylamide gel electrophoresis pmc beta search chronic myeloid leukemia p53-independent p21 inducer sti-571/imatinib resistance revealed chronic myeloid leukaemia publisher site pdf conjugated igg antibody cyclin dependent kinase chronic myelocytic leukaemia transactivated p21 promoter activates p21 promoter license information pmcid amersham pharmacia biotech phosphatidylinositol 3-kinase inhibitor anti-β-actin relative luciferase activity increased time-dependently p21-related biology suppress kinase activity cell cycle progression anti-proliferative activity wst-8 assay kit united states government myeloproliferative disease originating made great progress tianjin medical university semisynthetic process solves p53-dependent manner anti-proliferative effect luciferase assay system p21-transactivating activity induce p21 expression cellphect transfection kit daiichi pure chemicals wing low software western blot analysis antitumor drug candidates p53-independent manner induces g1 arrest sponge aaptos suberitoides induces erythroid differentiation
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- Chronic myeloid leukemia 2010: Where are we now and where can we go?
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