
NCBI . NLM . NIH . GOV {
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Title[redir]:
Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still's disease: a case-series study - PMC
Description:
To assess the efficacy and safety of the interleukin-1 receptor (IL-1R) inhibitor anakinra in adult patients with refractory Still
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Keywords {🔍}
patients, disease, months, treatment, anakinra, response, patient, doi, stills, follow, clinical, complete, laboratory, pubmed, google, scholar, activity, median, mtx, month, levels, time, arthritis, study, adult, drug, table, crp, partial, ferritin, pmc, esr, rheum, therapy, remission, efficacy, dose, pcr, plr, reported, article, refractory, parameters, data, fever, acr, elevated, anemia, vas, ilr,
Topics {✒️}
disease-modifying anti-rheumatic drugs disease-modifying anti-rheumatic drug steroidal anti-inflammatory drugs pmc beta search competing interests elevated acute-phase proteins human il-1r antagonist elevated acute-phase reactants il-1r inhibitor points demonstrated high il-1a il1-receptor antagonist anakinra anti-il1 drug anakinra drug-related adverse events methods patient selection anti-interleukin-1 treatment distinguishes license information pmcid references pouchot effective steroid-sparing agent abbreviations acr il-1r inhibitor anakinra dinarello ca steroid refractory adult-onset laboratory disease-related manifestations hemophagocytic syndrome complicating publisher site pdf il-1ra therapy due acute-phase reactants steroid-sparing drugs acute inflammatory response symptoms automatically resolved methods twenty tumor necrosis factor tumour necrosis factor health assessment questionnaire upper respiratory tract authors declare authors read serial cytokine measurements treatment-resistant adult-onset persisting biological activity traditional immunosuppressive drugs pmc disclaimer il-1r inhibitor [15] drug-related complications visualized analogue scale visual analogue scale persisting clinical symptoms interleukin-1 receptor antagonist united states government quotidian spiking fevers
Questions {❓}
- Refractory adult onset Still's disease and hypersensitivity to non-steroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors: are biological agents the solution?
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