
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Genetics and pathogenesis of inflammatory bowel disease - PMC
Description:
Recent advances have provided substantial insight into the maintenance of mucosal immunity and the pathogenesis of inflammatory bowel disease. Cellular programs responsible for intestinal homeostasis use diverse intracellular and intercellular ...
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🌠 Phenomenal Traffic: 5M - 10M visitors per month
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Keywords {🔍}
doi, cells, pubmed, google, scholar, disease, ibd, pmc, article, free, intestinal, colitis, immune, crohns, nature, genetic, cell, microbial, genes, mice, loci, pathways, nod, studies, epithelial, variants, responses, patients, gut, host, innate, ulcerative, response, production, inflammation, factors, homeostasis, including, signalling, inflammatory, effects, function, bacterial, risk, susceptibility, autophagy, receptor, differentiation, microbiota, immunity,
Topics {✒️}
vascular-endothelial-growth-factor-secreting ly6clow monocytes genome-wide meta-analysis increases iec-specific atg5-deficient mice27 dendritic-cell-specific icam3-grabbing pro-inflammatory nf-κb-dependent cytokines il-1β-secreting ly6chigh monocytes hepatocyte nuclear factor-4α affect transcription-factor-binding sequences inhibits tight-junction assembly pro-inflammatory cytokine il-17a mis-localised cytoplasmic protein anti-inflammatory treg-cell effects germ-free mice reveals g-protein-coupled receptor extracellular acidification-induced inhibition g-protein-coupled receptors disparate t-cell fates genome-wide association scan glutathione s-transferase enzymes tumour-necrosis factor-α transforming growth factor-β pore-forming hydrophobic peptides intestinal stem-cell niche quorum-sensing molecule pmc beta search drives treg-cell differentiation lysosomal α-galactosidase controls intestinal alkaline phosphatase early b-cell selection selectively engaging pro-inflammatory crohn’s-disease-related polymorphisms promote th17-cell differentiation44 short-chain fatty acid exert anti-inflammatory activities t-cell education programs tgf-β-rich milieu limit treg-cell differentiation synthesizing anti-inflammatory mediators t-cell-independent iga inadequate treg-cell response allele-specific gene-expression short-chain fatty acids α-defensin-related sequence 10 promotes th17-cell differentiation malt1 controls anti-fungal genome-wide association studies secrete anti-inflammatory cytokines peripheral b-cell tolerance th17–treg-cell axis ibd-implicated adaptor protein
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- What's the income of https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20Sci%20USA&title=Induction%20of%20regulatory%20T%20cells%20by%20macrophages%20is%20dependent%20on%20production%20of%20reactive%20oxygen%20species&author=MD%20Kraaij&volume=107&publication_year=2010&pages=17686-17691&pmid=20861446&doi=10.1073/pnas.1012016107&?
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- Income figures for https://scholar.google.com/scholar_lookup?journal=Nature%20Genet&title=Genome-wide%20association%20study%20identifies%20new%20susceptibility%20loci%20for%20Crohn%20disease%20and%20implicates%20autophagy%20in%20disease%20pathogenesis&author=JD%20Rioux&volume=39&publication_year=2007&pages=596-604&pmid=17435756&doi=10.1038/ng2032&
- https://doi.org/10.1038/ng1954's revenue stream
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- Explore the financials of https://scholar.google.com/scholar_lookup?journal=PLoS%20ONE&title=Impaired%20autophagy%20of%20an%20intracellular%20pathogen%20induced%20by%20a%20Crohn%E2%80%99s%20disease%20associated%20ATG16L1%20variant&author=P%20Kuballa&author=A%20Huett&author=JD%20Rioux&author=MJ%20Daly&author=RJ%20Xavier&volume=3&publication_year=2008&pages=e3391&pmid=18852889&doi=10.1371/journal.pone.0003391&
- How much money does https://doi.org/10.1016/j.cell.2010.05.009 make?
- Explore the financials of https://scholar.google.com/scholar_lookup?journal=Cell&title=Virus-plus-susceptibility%20gene%20interaction%20determines%20Crohn%E2%80%99s%20disease%20gene%20Atg16L1%20phenotypes%20in%20intestine&author=K%20Cadwell&volume=141&publication_year=2010&pages=1135-1145&pmid=20602997&doi=10.1016/j.cell.2010.05.009&
- Revenue of https://doi.org/10.1038/nature06878
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Nature&title=TGF-%CE%B2-induced%20Foxp3%20inhibits%20TH17%20cell%20differentiation%20by%20antagonizing%20ROR%CE%B3t%20function&author=L%20Zhou&volume=453&publication_year=2008&pages=236-240&pmid=18368049&doi=10.1038/nature06878& produce monthly?
- What's the financial intake of https://doi.org/10.1038/ni.2006?
- How much income does https://scholar.google.com/scholar_lookup?journal=Nature%20Immunol&title=The%20transcription%20factors%20Blimp-1%20and%20IRF4%20jointly%20control%20the%20differentiation%20and%20function%20of%20effector%20regulatory%20T%20cells&author=E%20Cretney&volume=12&publication_year=2011&pages=304-311&pmid=21378976&doi=10.1038/ni.2006& have?
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- https://scholar.google.com/scholar_lookup?journal=Nature&title=Generation%20of%20pathogenic%20TH17%20cells%20in%20the%20absence%20of%20TGF-%CE%B2%20signalling&author=K%20Ghoreschi&volume=467&publication_year=2010&pages=967-971&pmid=20962846&doi=10.1038/nature09447&'s financial summary
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- How profitable is https://scholar.google.com/scholar_lookup?journal=Immunity&title=Foxp3+%20regulatory%20T%20cells%20promote%20T%20helper%2017%20cell%20development%20in%20vivo%20through%20regulation%20of%20interleukin-2&author=Y%20Chen&volume=34&publication_year=2011&pages=409-421&pmid=21435588&doi=10.1016/j.immuni.2011.02.011&?
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- What's the revenue for https://scholar.google.com/scholar_lookup?journal=Nature%20Immunol&title=Identification%20of%20a%20human%20helper%20T%20cell%20population%20that%20has%20abundant%20production%20of%20interleukin%2022%20and%20is%20distinct%20from%20TH-17,%20TH1%20and%20TH2%20cells&author=S%20Trifari&author=CD%20Kaplan&author=EH%20Tran&author=NK%20Crellin&author=H%20Spits&volume=10&publication_year=2009&pages=864-871&pmid=19578368&doi=10.1038/ni.1770&?
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- How much cash flow does https://doi.org/10.1038/mi.2010.69 have monthly?
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- Earnings of https://doi.org/10.1038/ng.644
- Financial intake of https://scholar.google.com/scholar_lookup?journal=Nature%20Genet&title=Association%20of%20IFIH1%20and%20other%20autoimmunity%20risk%20alleles%20with%20selective%20IgA%20deficiency&author=RC%20Ferreira&volume=42&publication_year=2010&pages=777-780&pmid=20694011&doi=10.1038/ng.644&
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- How profitable is https://scholar.google.com/scholar_lookup?journal=Nature&title=Functionally%20defective%20germline%20variants%20of%20sialic%20acid%20acetylesterase%20in%20autoimmunity&author=I%20Surolia&volume=466&publication_year=2010&pages=243-247&pmid=20555325&doi=10.1038/nature09115&?
- Monthly income for https://doi.org/10.1016/j.immuni.2009.11.009
- What's the income of https://scholar.google.com/scholar_lookup?journal=Immunity&title=CD19+CD24hiCD38hi%20B%20cells%20exhibit%20regulatory%20capacity%20in%20healthy%20individuals%20but%20are%20functionally%20impaired%20in%20systemic%20lupus%20erythematosus%20patients&author=PA%20Blair&volume=32&publication_year=2010&pages=129-140&pmid=20079667&doi=10.1016/j.immuni.2009.11.009&?
- Income figures for https://doi.org/10.1038/ni.1997
- How much does https://scholar.google.com/scholar_lookup?journal=Nature%20Immunol&title=Control%20of%20the%20development%20of%20CD8%CE%B1%CE%B1+%20intestinal%20intraepithelial%20lymphocytes%20by%20TGF-%CE%B2&author=JE%20Konkel&volume=12&publication_year=2011&pages=312-319&pmid=21297643&doi=10.1038/ni.1997& make?
- What's https://doi.org/10.1016/j.immuni.2010.08.003's gross income?
- How much money does https://scholar.google.com/scholar_lookup?journal=Immunity&title=Lysosomal%20%CE%B1-galactosidase%20controls%20the%20generation%20of%20self%20lipid%20antigens%20for%20natural%20killer%20T%20cells&author=A%20Darmoise&volume=33&publication_year=2010&pages=216-228&pmid=20727792&doi=10.1016/j.immuni.2010.08.003& make?
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- https://scholar.google.com/scholar_lookup?journal=Semin%20Oncol&title=Ipilimumab:%20unleashing%20the%20power%20of%20the%20immune%20system%20through%20CTLA-4%20blockade&author=P%20Boasberg&author=O%20Hamid&author=S%20O%E2%80%99Day&volume=37&publication_year=2010&pages=440-449&pmid=21074058&doi=10.1053/j.seminoncol.2010.09.004&'s financial summary
- Find out how much https://doi.org/10.1073/pnas.1002355107 earns monthly
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- Find out how much https://doi.org/10.1016/j.cell.2007.08.017 earns monthly
- What's the income of https://scholar.google.com/scholar_lookup?journal=Cell&title=Communicable%20ulcerative%20colitis%20induced%20by%20T-bet%20deficiency%20in%20the%20innate%20immune%20system&author=WS%20Garrett&volume=131&publication_year=2007&pages=33-45&pmid=17923086&doi=10.1016/j.cell.2007.08.017&?
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- How much does https://doi.org/10.1038/ni.1991 rake in every month?
- Income figures for https://scholar.google.com/scholar_lookup?journal=Nature%20Immunol&title=Mice%20carrying%20a%20knock-in%20mutation%20of%20Aicda%20resulting%20in%20a%20defect%20in%20somatic%20hypermutation%20have%20impaired%20gut%20homeostasis%20and%20compromised%20mucosal%20defense&author=M%20Wei&volume=12&publication_year=2011&pages=264-270&pmid=21258321&doi=10.1038/ni.1991&
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- How much does https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=Involvement%20of%20proton-sensing%20TDAG8%20in%20extracellular%20acidification-induced%20inhibition%20of%20proinflammatory%20cytokine%20production%20in%20peritoneal%20macrophages&author=C%20Mogi&volume=182&publication_year=2009&pages=3243-3251&pmid=19234222&doi=10.4049/jimmunol.0803466& earn?
- https://doi.org/10.1016/j.chom.2007.05.004 income
- How much does https://scholar.google.com/scholar_lookup?journal=Cell%20Host%20Microbe&title=The%20Bacillus%20subtilis%20quorum-sensing%20molecule%20CSF%20contributes%20to%20intestinal%20homeostasis%20via%20OCTN2,%20a%20host%20cell%20membrane%20transporter&author=M%20Fujiya&volume=1&publication_year=2007&pages=299-308&pmid=18005709&doi=10.1016/j.chom.2007.05.004& earn?
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- What are the total earnings of https://doi.org/10.1073/pnas.1014669107?
- How much revenue does https://scholar.google.com/scholar_lookup?journal=Proc%20Natl%20Acad%20USA&title=MyD88%20signaling%20in%20nonhematopoietic%20cells%20protects%20mice%20against%20induced%20colitis%20by%20regulating%20specific%20EGF%20receptor%20ligands&author=K%20Brandl&volume=107&publication_year=2010&pages=19967-19972&pmid=21041656&doi=10.1073/pnas.1014669107& generate?
- Get to know what's the income of https://doi.org/10.4049/jimmunol.1003888
- How much does https://scholar.google.com/scholar_lookup?journal=J%20Immunol&title=NFIL3%20is%20a%20regulator%20of%20IL-12%20p40%20in%20macrophages%20and%20mucosal%20immunity&author=T%20Kobayashi&volume=186&publication_year=2011&pages=4649-4655&pmid=21383239&doi=10.4049/jimmunol.1003888& make?
- Check the income stats for https://doi.org/10.1016/j.cell.2009.09.033
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