
NCBI . NLM . NIH . GOV {
}
Title[redir]:
Molecular mechanisms of long noncoding RNAs - PMC
Description:
Long noncoding RNAs (lncRNAs) are an important class of pervasive genes involved in a variety of biological functions. Here we discuss the emerging archetypes of molecular functions that lncRNAs execute—as signals, decoys, guides, and scaffolds. For ...
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Keywords {🔍}
doi, rna, pubmed, google, scholar, lncrnas, lncrna, gene, noncoding, pmc, expression, article, chromatin, free, cell, transcription, genes, rnas, regulation, transcriptional, long, regulatory, archetype, silencing, target, prc, function, binding, protein, promoter, telomerase, molecular, dna, proteins, xist, complexes, nature, complex, mechanism, specific, histone, cis, hotair, polycomb, multiple, repression, cells, human, locus, mechanisms,
Topics {✒️}
apc-cdh1 tumor-suppressive complex half-stau1-binding site rnas cell cycle-dependent manner—accumulating pmc beta search ink4b/arf/ink4a locus recent high-throughput studies p53 regulates linc-p21 tumor-suppressor protein pten tumor-suppressor gene pten conserved multi-exonic structure cell type-specific transcriptomes lincrna-p21 increases expression environmentally-induced epigenetic switch numerous p53-repressed transcripts transcription factor nf-ya xrn1-sensitive antisense regulatory phosphate-starvation inducible mir-399 induce cold-dependent silencing cell cycle-dependent manner species-specific accessory proteins noncoding rna-mediated targeting genome-wide epigenetic reprogramming common disease-association studies anterior-posterior anatomic axis post-transcriptional gene silencing repressive histone-modifying activities neuronal activity-regulated enhancers multiple chromatin-modifying complexes dna-protein complexes located long nuclear-retained antisense noncoding rna franco-zorrilla long range actions polycomb-dependent regulatory contacts functional multi-functional lncrna chromosome-wide silencing step tumor suppressor gene coding rna-dna complex neighboring protein-coding genes rna-based transcript regulators comprehensive structure-function analysis guide—rna binds protein long antisense transcripts post-transcriptional gene regulation vernalization-mediated epigenetic silencing rna-binding protein tls nuclear pten regulates van de ven template boundary definition rna-dna triplex structure
Questions {❓}
- RNA regulation: a new genetics?
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